UniProt functional annotation for P16458

UniProt code: P16458.

Organism: Sterkiella nova (Ciliate) (Oxytricha nova).
Taxonomy: Eukaryota; Sar; Alveolata; Ciliophora; Intramacronucleata; Spirotrichea; Stichotrichia; Sporadotrichida; Oxytrichidae; Stylonychinae; Sterkiella.
 
Function: May function as protective capping of the single-stranded telomeric overhang. May also participate in telomere length regulation during DNA replication. Binds specifically to the T4G4-containing extension on the 3'strand and protects this region of the telomere from nuclease digestion and chemical modification.
 
Subunit: Heterodimer of an alpha and a beta subunit.
Subcellular location: Nucleus. Chromosome, telomere.
Miscellaneous: The sequence of MAC-41A is shown. MAC-41S differs in only one position.

Annotations taken from UniProtKB at the EBI.