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UniProt functional annotation for P62577 | ||
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| UniProt code: P62577. |
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| Organism: | |
Escherichia coli. |
| Taxonomy: | |
Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales; Enterobacteriaceae; Escherichia. |
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| Function: | |
This enzyme is an effector of chloramphenicol resistance in bacteria. |
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| Catalytic activity: | |
Reaction=acetyl-CoA + chloramphenicol = chloramphenicol 3-acetate + CoA; Xref=Rhea:RHEA:18421, ChEBI:CHEBI:16730, ChEBI:CHEBI:17698, ChEBI:CHEBI:57287, ChEBI:CHEBI:57288; EC=2.3.1.28; Evidence={ECO:0000255|PROSITE-ProRule:PRU10021}; |
| Subunit: | |
Homotrimer. {ECO:0000269|PubMed:9334294}. |
| Biotechnology: | |
This protein is used as a marker in many commonly used cloning vectors, such as pACYC184. |
| Miscellaneous: | |
Transposon Tncam204 is derived from the R plasmid NR1. {ECO:0000305|PubMed:7353655}. |
| Similarity: | |
Belongs to the chloramphenicol acetyltransferase family. {ECO:0000305}. |
Annotations taken from UniProtKB at the EBI.