UniProt functional annotation for P58315

UniProt code: P58315.

Organism: Thermoproteus tenax (strain ATCC 35583 / DSM 2078 / JCM 9277 / NBRC 100435 / Kra 1).
Taxonomy: Archaea; Crenarchaeota; Thermoprotei; Thermoproteales; Thermoproteaceae; Thermoproteus.
 
Function: Catalyzes the reversible cleavage of fructose 1,6- bisphosphate (FBP) to glyceraldehyde 3-phosphate (GAP) and dihydroxyacetone phosphate (DHAP).
 
Catalytic activity: Reaction=beta-D-fructose 1,6-bisphosphate = D-glyceraldehyde 3- phosphate + dihydroxyacetone phosphate; Xref=Rhea:RHEA:14729, ChEBI:CHEBI:32966, ChEBI:CHEBI:57642, ChEBI:CHEBI:59776; EC=4.1.2.13; Evidence={ECO:0000269|PubMed:11387336};
Activity regulation: Activated by citrate. {ECO:0000269|PubMed:11387336}.
Subunit: Homodecamer (dimer of pentamers). {ECO:0000269|PubMed:11387336, ECO:0000269|PubMed:12941964, ECO:0000269|PubMed:15766250}.
Subcellular location: Cytoplasm {ECO:0000305}.
Similarity: Belongs to the DeoC/FbaB aldolase family. {ECO:0000305}.

Annotations taken from UniProtKB at the EBI.