UniProt functional annotation for P0A112



	UniProt functional annotation for P0A112

UniProt code: P0A112.

Organism: Pseudomonas putida (Arthrobacter siderocapsulatus).

Taxonomy: Bacteria; Proteobacteria; Gammaproteobacteria; Pseudomonadales; Pseudomonadaceae; Pseudomonas.

Function: Component of the naphthalene dioxygenase (NDO) multicomponent enzyme system which catalyzes the incorporation of both atoms of molecular oxygen into naphthalene to form cis-(1R,2S)-dihydroxy-1,2- dihydronaphthalene. The beta subunit seems to have a structural role in the holoenzyme. Also able to catalyze the cis-dihydroxylation of biphenyl and phenanthrene (PubMed:10692370). {ECO:0000269|PubMed:10692370, ECO:0000269|PubMed:6874638}.

Pathway: Aromatic compound metabolism; naphthalene degradation. {ECO:0000305|PubMed:10692370}.

Subunit: The naphthalene dioxygenase (NDO) multicomponent enzyme system is composed of an electron transfer component and a dioxygenase component (iron sulfur protein (ISP)). The electron transfer component is composed of a ferredoxin reductase (NdoR) and a ferredoxin (NdoA), and the dioxygenase component is formed of a heterohexamer (trimer of heterodimers) of three large alpha subunits (NdoB) and three small beta subunits (NdoC). {ECO:0000269|PubMed:12586937, ECO:0000269|PubMed:15942729, ECO:0000269|PubMed:9634695, ECO:0000305|PubMed:6874638}.

Similarity: Belongs to the bacterial ring-hydroxylating dioxygenase beta subunit family. {ECO:0000305}.

Annotations taken from UniProtKB at the EBI.


Organism:		Pseudomonas putida (Arthrobacter siderocapsulatus).
Taxonomy:		Bacteria; Proteobacteria; Gammaproteobacteria; Pseudomonadales; Pseudomonadaceae; Pseudomonas.



Function:		Component of the naphthalene dioxygenase (NDO) multicomponent enzyme system which catalyzes the incorporation of both atoms of molecular oxygen into naphthalene to form cis-(1R,2S)-dihydroxy-1,2- dihydronaphthalene. The beta subunit seems to have a structural role in the holoenzyme. Also able to catalyze the cis-dihydroxylation of biphenyl and phenanthrene (PubMed:10692370). {ECO:0000269\|PubMed:10692370, ECO:0000269\|PubMed:6874638}.


Pathway:		Aromatic compound metabolism; naphthalene degradation. {ECO:0000305\|PubMed:10692370}.
Subunit:		The naphthalene dioxygenase (NDO) multicomponent enzyme system is composed of an electron transfer component and a dioxygenase component (iron sulfur protein (ISP)). The electron transfer component is composed of a ferredoxin reductase (NdoR) and a ferredoxin (NdoA), and the dioxygenase component is formed of a heterohexamer (trimer of heterodimers) of three large alpha subunits (NdoB) and three small beta subunits (NdoC). {ECO:0000269\|PubMed:12586937, ECO:0000269\|PubMed:15942729, ECO:0000269\|PubMed:9634695, ECO:0000305\|PubMed:6874638}.
Similarity:		Belongs to the bacterial ring-hydroxylating dioxygenase beta subunit family. {ECO:0000305}.