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UniProt functional annotation for P80098 | ||
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| UniProt code: P80098. |
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| Organism: | |
Homo sapiens (Human). |
| Taxonomy: | |
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo. |
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| Function: | |
Chemotactic factor that attracts monocytes and eosinophils, but not neutrophils. Augments monocyte anti-tumor activity. Also induces the release of gelatinase B. This protein can bind heparin. Binds to CCR1, CCR2 and CCR3. |
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| Subunit: | |
Monomer. {ECO:0000269|PubMed:8898111}. |
| Subcellular location: | |
Secreted. |
| Ptm: | |
O-glycosylated. |
| Similarity: | |
Belongs to the intercrine beta (chemokine CC) family. {ECO:0000305}. |
| Sequence caution: | |
Sequence=CAA50405.1; Type=Erroneous initiation; Evidence={ECO:0000305}; Sequence=CAA50406.1; Type=Erroneous initiation; Evidence={ECO:0000305}; Sequence=CAA51055.1; Type=Erroneous initiation; Evidence={ECO:0000305}; |
Annotations taken from UniProtKB at the EBI.