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UniProt functional annotation for P37028 | ||
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| UniProt code: P37028. |
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| Organism: | |
Escherichia coli (strain K12). |
| Taxonomy: | |
Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales; Enterobacteriaceae; Escherichia. |
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| Function: | |
Part of the ABC transporter complex BtuCDF involved in vitamin B12 import. Binds vitamin B12 and delivers it to the periplasmic surface of BtuC. {ECO:0000255|HAMAP-Rule:MF_01000, ECO:0000269|PubMed:11790740}. |
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| Subunit: | |
The complex is composed of two ATP-binding proteins (BtuD), two transmembrane proteins (BtuC) and a solute-binding protein (BtuF). {ECO:0000255|HAMAP-Rule:MF_01000, ECO:0000269|PubMed:12468528, ECO:0000269|PubMed:12475936}. |
| Subcellular location: | |
Periplasm {ECO:0000255|HAMAP-Rule:MF_01000, ECO:0000269|PubMed:11790740}. |
| Miscellaneous: | |
Vitamin B12 is bound in a deep cleft formed at the interface between the two lobes of BtuF. {ECO:0000269|PubMed:12475936}. |
| Similarity: | |
Belongs to the BtuF family. {ECO:0000255|HAMAP- Rule:MF_01000, ECO:0000305}. |
Annotations taken from UniProtKB at the EBI.