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UniProt functional annotation for P02703 | ||
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| UniProt code: P02703. |
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| Organism: | |
Sus scrofa (Pig). |
| Taxonomy: | |
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Artiodactyla; Suina; Suidae; Sus. |
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| Function: | |
Colipase is a cofactor of pancreatic lipase. It allows the lipase to anchor itself to the lipid-water interface. Without colipase the enzyme is washed off by bile salts, which have an inhibitory effect on the lipase. {ECO:0000250|UniProtKB:P04118}. |
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| Function: | |
Enterostatin has a biological activity as a satiety signal. {ECO:0000250|UniProtKB:P04118}. |
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| Subunit: | |
Forms a 1:1 stoichiometric complex with pancreatic lipase. {ECO:0000255|PROSITE-ProRule:PRU00674, ECO:0000269|PubMed:1522902, ECO:0000269|PubMed:7773176, ECO:0000269|PubMed:8479519, ECO:0000269|PubMed:8663362}. |
| Subcellular location: | |
Secreted. |
| Tissue specificity: | |
Expressed by the pancreas. |
| Similarity: | |
Belongs to the colipase family. {ECO:0000255|PROSITE- ProRule:PRU00674}. |
Annotations taken from UniProtKB at the EBI.