UniProt functional annotation for P24146

UniProt code: P24146.

Organism: Griffonia simplicifolia (Bandeiraea simplicifolia).
Taxonomy: Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; fabids; Fabales; Fabaceae; Cercidoideae; Cercideae; Cercidinae; Griffonia.
 
Function: Lectin which has a strong affinity for both the Lewis b and y human blood-group determinants. {ECO:0000269|PubMed:8478943}.
 
Subunit: Homodimer of Alpha and Beta forms. {ECO:0000269|PubMed:8478943}.
Ptm: N-glycosylation of Asn-5 converts form Beta to form Alpha.
Miscellaneous: Binds one manganese (or another transition metal) ion and one calcium ion. The metal ions are essential for the saccharide- binding and cell-agglutinating activities. {ECO:0000269|PubMed:8478943}.
Similarity: Belongs to the leguminous lectin family. {ECO:0000305}.

Annotations taken from UniProtKB at the EBI.