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UniProt functional annotation for Q58989 | ||
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| UniProt code: Q58989. |
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| Organism: | |
Methanocaldococcus jannaschii (strain ATCC 43067 / DSM 2661 / JAL-1 / JCM 10045 / NBRC 100440) (Methanococcus jannaschii). |
| Taxonomy: | |
Archaea; Euryarchaeota; Methanomada group; Methanococci; Methanococcales; Methanocaldococcaceae; Methanocaldococcus. |
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| Catalytic activity: | |
Reaction=H2O + O-phospho-L-serine = L-serine + phosphate; Xref=Rhea:RHEA:21208, ChEBI:CHEBI:15377, ChEBI:CHEBI:33384, ChEBI:CHEBI:43474, ChEBI:CHEBI:57524; EC=3.1.3.3; Evidence={ECO:0000269|PubMed:11438683, ECO:0000269|PubMed:12051918}; |
| Catalytic activity: | |
Reaction=H2O + O-phospho-D-serine = D-serine + phosphate; Xref=Rhea:RHEA:24873, ChEBI:CHEBI:15377, ChEBI:CHEBI:35247, ChEBI:CHEBI:43474, ChEBI:CHEBI:58680; EC=3.1.3.3; Evidence={ECO:0000269|PubMed:11438683, ECO:0000269|PubMed:12051918}; |
| Cofactor: | |
Name=Mg(2+); Xref=ChEBI:CHEBI:18420; Evidence={ECO:0000269|PubMed:12051918}; Note=Binds 1 Mg(2+) ion per subunit. {ECO:0000269|PubMed:12051918}; |
| Biophysicochemical properties: | |
Kinetic parameters: KM=620 uM for O-phospho-L-serine (at 70 degrees Celsius and at pH 7.5) {ECO:0000269|PubMed:12051918}; pH dependence: Optimum pH is 7.5. {ECO:0000269|PubMed:12051918}; Temperature dependence: Optimum temperature is 70 degrees Celsius. {ECO:0000269|PubMed:12051918}; |
| Pathway: | |
Amino-acid biosynthesis; L-serine biosynthesis; L-serine from 3-phospho-D-glycerate: step 3/3. |
| Similarity: | |
Belongs to the HAD-like hydrolase superfamily. SerB family. {ECO:0000305}. |
Annotations taken from UniProtKB at the EBI.