UniProt functional annotation for P0C2S5

UniProt code: P0C2S5.

Organism: Hungateiclostridium thermocellum (Clostridium thermocellum).
Taxonomy: Bacteria; Firmicutes; Clostridia; Eubacteriales; Oscillospiraceae; Acetivibrio.
 
Function: This enzyme catalyzes the exohydrolysis of 1,4-beta- glucosidic linkages in cellulose with a preference for amorphous or crystalline cellulose over carboxymethyl cellulose. {ECO:0000269|PubMed:20967294}.
 
Catalytic activity: Reaction=Hydrolysis of (1->4)-beta-D-glucosidic linkages in cellulose and similar substrates, releasing cellobiose from the reducing ends of the chains.; EC=3.2.1.176; Evidence={ECO:0000269|PubMed:20967294};
Activity regulation: Inhibited by cellobiose and lactose, but not by glucose. {ECO:0000250}.
Subcellular location: Secreted.
Similarity: Belongs to the glycosyl hydrolase 48 (cellulase L) family. {ECO:0000305}.

Annotations taken from UniProtKB at the EBI.