UniProt functional annotation for Q8ZRP8

UniProt code: Q8ZRP8.

Organism: Salmonella typhimurium (strain LT2 / SGSC1412 / ATCC 700720).
Taxonomy: Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales; Enterobacteriaceae; Salmonella.
 
Function: Proton-coupled chloride transporter. Functions as antiport system and exchanges two chloride ions for 1 proton. Probably acts as an electrical shunt for an outwardly-directed proton pump that is linked to amino acid decarboxylation, as part of the extreme acid resistance (XAR) response. {ECO:0000269|PubMed:11796999}.
 
Subunit: Homodimer.
Subcellular location: Cell inner membrane {ECO:0000305}; Multi-pass membrane protein {ECO:0000305}.
Similarity: Belongs to the chloride channel (TC 2.A.49) family. ClcA subfamily. {ECO:0000305}.

Annotations taken from UniProtKB at the EBI.