| UniProt functional annotation for P59846 | |||
| UniProt code: P59846. |
| Organism: | Thermus thermophilus (strain ATCC 27634 / DSM 579 / HB8). | |
| Taxonomy: | Bacteria; Deinococcus-Thermus; Deinococci; Thermales; Thermaceae; Thermus. | |
| Catalytic activity: | Reaction=ATP + L-aspartate + L-citrulline = 2-(N(omega)-L- arginino)succinate + AMP + diphosphate + H(+); Xref=Rhea:RHEA:10932, ChEBI:CHEBI:15378, ChEBI:CHEBI:29991, ChEBI:CHEBI:30616, ChEBI:CHEBI:33019, ChEBI:CHEBI:57472, ChEBI:CHEBI:57743, ChEBI:CHEBI:456215; EC=6.3.4.5; Evidence={ECO:0000255|HAMAP- Rule:MF_00005}; | |
| Pathway: | Amino-acid biosynthesis; L-arginine biosynthesis; L-arginine from L-ornithine and carbamoyl phosphate: step 2/3. {ECO:0000255|HAMAP- Rule:MF_00005}. | |
| Subunit: | Homotetramer. {ECO:0000255|HAMAP-Rule:MF_00005, ECO:0000269|PubMed:11844799, ECO:0000269|PubMed:12684518}. | |
| Subcellular location: | Cytoplasm {ECO:0000305}. | |
| Similarity: | Belongs to the argininosuccinate synthase family. Type 1 subfamily. {ECO:0000255|HAMAP-Rule:MF_00005}. | |
Annotations taken from UniProtKB at the EBI.