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UniProt functional annotation for Q10423 | ||
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| UniProt code: Q10423. |
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| Organism: | |
Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast). |
| Taxonomy: | |
Eukaryota; Fungi; Dikarya; Ascomycota; Taphrinomycotina; Schizosaccharomycetes; Schizosaccharomycetales; Schizosaccharomycetaceae; Schizosaccharomyces. |
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| Function: | |
Capable of resolving Holliday junctions. Specific for 4-way junctions. Seems to be important for the maintenance of mitochondrial DNA. Cleaves fixed junctions at the point of strand exchange. Cleaves after 5'-CT-3' and 5'-TT-3' sequences. {ECO:0000269|PubMed:10954073, ECO:0000269|PubMed:9343409}. |
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| Catalytic activity: | |
Reaction=Endonucleolytic cleavage at a junction such as a reciprocal single-stranded crossover between two homologous DNA duplexes (Holliday junction).; EC=3.1.22.4; Evidence={ECO:0000269|PubMed:9343409}; |
| Subunit: | |
Homodimer. {ECO:0000269|PubMed:9343409}. |
| Subcellular location: | |
Mitochondrion {ECO:0000269|PubMed:10954073}. |
Annotations taken from UniProtKB at the EBI.