|
|
||
|
|
|
|
|
UniProt functional annotation for Q5SLL5 | ||
|
|
|
|
|
|
||
| UniProt code: Q5SLL5. |
|
||
| Organism: | |
Thermus thermophilus (strain ATCC 27634 / DSM 579 / HB8). |
| Taxonomy: | |
Bacteria; Deinococcus-Thermus; Deinococci; Thermales; Thermaceae; Thermus. |
|
||
|
||
| Function: | |
Involved in gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA (By similarity). {ECO:0000250, ECO:0000269|PubMed:16239727}. |
|
||
| Catalytic activity: | |
Reaction=ATP + oxaloacetate = ADP + CO2 + phosphoenolpyruvate; Xref=Rhea:RHEA:18617, ChEBI:CHEBI:16452, ChEBI:CHEBI:16526, ChEBI:CHEBI:30616, ChEBI:CHEBI:58702, ChEBI:CHEBI:456216; EC=4.1.1.49; Evidence={ECO:0000255|HAMAP-Rule:MF_00453}; |
| Cofactor: | |
Name=Mn(2+); Xref=ChEBI:CHEBI:29035; Evidence={ECO:0000255|HAMAP-Rule:MF_00453}; Note=Binds 1 Mn(2+) ion per subunit. {ECO:0000255|HAMAP-Rule:MF_00453}; |
| Activity regulation: | |
Allosterically activated by calcium. {ECO:0000250}. |
| Pathway: | |
Carbohydrate biosynthesis; gluconeogenesis. {ECO:0000255|HAMAP-Rule:MF_00453}. |
| Subunit: | |
Dimer of dimers. {ECO:0000305|PubMed:16239727, ECO:0000305|Ref.3}. |
| Subcellular location: | |
Cytoplasm {ECO:0000255|HAMAP-Rule:MF_00453}. |
| Similarity: | |
Belongs to the phosphoenolpyruvate carboxykinase (ATP) family. {ECO:0000255|HAMAP-Rule:MF_00453}. |
Annotations taken from UniProtKB at the EBI.