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UniProt functional annotation for P01563 | ||
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| UniProt code: P01563. |
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| Organism: | |
Homo sapiens (Human). |
| Taxonomy: | |
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo. |
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| Function: | |
Produced by macrophages, IFN-alpha have antiviral activities. |
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| Subunit: | |
Interacts with IFNAR2. {ECO:0000269|PubMed:17001036, ECO:0000269|PubMed:20496919}. |
| Subcellular location: | |
Secreted. |
| Polymorphism: | |
Three forms exist; alpha-2a (shown here), alpha-2b and alpha-2c (PubMed:7627809). {ECO:0000269|PubMed:7627809}. |
| Pharmaceutical: | |
Available under the names Roferon-A (Roche) or Intron-A (Schering-Plough). Used as an anticancer drug for its antiproliferative activity. |
| Similarity: | |
Belongs to the alpha/beta interferon family. {ECO:0000305}. |
Annotations taken from UniProtKB at the EBI.