| UniProt functional annotation for P07598 | |||
| UniProt code: P07598. |
| Organism: | Desulfovibrio vulgaris (strain ATCC 29579 / DSM 644 / NCIMB 8303 / VKM B-1760 / Hildenborough). | |
| Taxonomy: | Bacteria; Proteobacteria; Deltaproteobacteria; Desulfovibrionales; Desulfovibrionaceae; Desulfovibrio. | |
| Function: | May be involved in hydrogen uptake for the reduction of sulfate to hydrogen sulfide in an electron transport chain. Cytochrome c3 is likely to be the physiological electron carrier for the enzyme. | |
| Catalytic activity: | Reaction=H2 + 2 oxidized [2Fe-2S]-[ferredoxin] = 2 H(+) + 2 reduced [2Fe-2S]-[ferredoxin]; Xref=Rhea:RHEA:17445, Rhea:RHEA-COMP:10000, Rhea:RHEA-COMP:10001, ChEBI:CHEBI:15378, ChEBI:CHEBI:18276, ChEBI:CHEBI:33737, ChEBI:CHEBI:33738; EC=1.12.7.2; | |
| Cofactor: | Name=[4Fe-4S] cluster; Xref=ChEBI:CHEBI:49883; Evidence={ECO:0000269|PubMed:10368269}; Note=Binds 3 [4Fe-4S] clusters per subunit. {ECO:0000269|PubMed:10368269}; | |
| Cofactor: | Name=Fe(2+); Xref=ChEBI:CHEBI:29033; Evidence={ECO:0000269|PubMed:10368269}; Note=Contains an active site Fe binuclear center, which is coordinated by Cys-382 and by non-protein ligands. {ECO:0000269|PubMed:10368269}; | |
| Subunit: | Heterodimer of a large and a small subunit. {ECO:0000269|PubMed:10368269}. | |
| Subcellular location: | Periplasm. | |
| Miscellaneous: | [Fe], [NiFe], and [NiFeSe] hydrogenases appear to represent three distinct enzymes having hydrogenase activity. | |
Annotations taken from UniProtKB at the EBI.