UniProt functional annotation for P52555

UniProt code: P52555.

Organism:		Rattus norvegicus (Rat).
Taxonomy:		Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus.
Function:		Does not seem to be a disulfide isomerase. Plays an important role in the processing of secretory proteins within the endoplasmic reticulum (ER), possibly by participating in the folding of proteins in the ER.
Subunit:		Homodimer. Part of a large chaperone multiprotein complex comprising CABP1, DNAJB11, HSP90B1, HSPA5, HYOU, PDIA2, PDIA4, PPIB, SDF2L1, UGGT1 and very small amounts of ERP29, but not, or at very low levels, CALR nor CANX (By similarity). {ECO:0000250}.
Subcellular location:		Endoplasmic reticulum lumen. Melanosome {ECO:0000250}.
Tissue specificity:		Ubiquitous. Mostly expressed in secretory tissues.
Induction:		By stress.

Annotations taken from UniProtKB at the EBI.