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UniProt functional annotation for P00929 | ||
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| UniProt code: P00929. |
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| Organism: | |
Salmonella typhimurium (strain LT2 / SGSC1412 / ATCC 700720). |
| Taxonomy: | |
Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales; Enterobacteriaceae; Salmonella. |
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| Function: | |
The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate. |
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| Catalytic activity: | |
Reaction=(1S,2R)-1-C-(indol-3-yl)glycerol 3-phosphate + L-serine = D- glyceraldehyde 3-phosphate + H2O + L-tryptophan; Xref=Rhea:RHEA:10532, ChEBI:CHEBI:15377, ChEBI:CHEBI:33384, ChEBI:CHEBI:57912, ChEBI:CHEBI:58866, ChEBI:CHEBI:59776; EC=4.2.1.20; Evidence={ECO:0000255|HAMAP-Rule:MF_00131}; |
| Pathway: | |
Amino-acid biosynthesis; L-tryptophan biosynthesis; L- tryptophan from chorismate: step 5/5. {ECO:0000255|HAMAP- Rule:MF_00131}. |
| Subunit: | |
Tetramer of two alpha and two beta chains. |
| Similarity: | |
Belongs to the TrpA family. {ECO:0000255|HAMAP- Rule:MF_00131}. |
Annotations taken from UniProtKB at the EBI.