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UniProt functional annotation for Q9S1E5 | ||
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| UniProt code: Q9S1E5. |
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| Organism: | |
Wolinella succinogenes (strain ATCC 29543 / DSM 1740 / LMG 7466 / NCTC 11488 / FDC 602W) (Vibrio succinogenes). |
| Taxonomy: | |
Bacteria; Proteobacteria; Epsilonproteobacteria; Campylobacterales; Helicobacteraceae; Wolinella. |
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| Function: | |
Catalyzes the reduction of nitrite to ammonia, consuming six electrons in the process. Has very low activity toward hydroxylamine, and even lower activity toward sulfite. Sulfite reductase activity is maximal at neutral pH. {ECO:0000269|PubMed:10672190, ECO:0000269|PubMed:18201106}. |
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| Catalytic activity: | |
Reaction=6 [Fe(III)cytochrome c] + 2 H2O + NH4(+) = 6 [Fe(II)cytochrome c] + 8 H(+) + nitrite; Xref=Rhea:RHEA:13089, Rhea:RHEA-COMP:10350, Rhea:RHEA-COMP:14399, ChEBI:CHEBI:15377, ChEBI:CHEBI:15378, ChEBI:CHEBI:16301, ChEBI:CHEBI:28938, ChEBI:CHEBI:29033, ChEBI:CHEBI:29034; EC=1.7.2.2; Evidence={ECO:0000269|PubMed:18201106}; |
| Cofactor: | |
Name=Ca(2+); Xref=ChEBI:CHEBI:29108; Evidence={ECO:0000269|PubMed:10984487, ECO:0000269|PubMed:12296741, ECO:0000269|PubMed:18201106}; Note=Binds 1 Ca(2+) ion per monomer. {ECO:0000269|PubMed:10984487, ECO:0000269|PubMed:12296741, ECO:0000269|PubMed:18201106}; |
| Cofactor: | |
Name=heme; Xref=ChEBI:CHEBI:30413; Evidence={ECO:0000269|PubMed:10984487, ECO:0000269|PubMed:12296741, ECO:0000269|PubMed:18201106}; Note=Binds 5 heme groups covalently per monomer. {ECO:0000269|PubMed:10984487, ECO:0000269|PubMed:12296741, ECO:0000269|PubMed:18201106}; |
| Pathway: | |
Nitrogen metabolism; nitrate reduction (assimilation). |
| Subunit: | |
Homodimer (PubMed:10984487, PubMed:12296741). Interacts with NrfH (PubMed:10672190). May form a heterotetramer with NrfH (PubMed:11807271). {ECO:0000269|PubMed:10672190, ECO:0000269|PubMed:10984487, ECO:0000269|PubMed:12296741, ECO:0000305|PubMed:11807271}. |
| Subcellular location: | |
Periplasm {ECO:0000269|PubMed:10672190, ECO:0000305|PubMed:10984487, ECO:0000305|PubMed:12296741}. |
| Similarity: | |
Belongs to the cytochrome c-552 family. {ECO:0000305}. |
Annotations taken from UniProtKB at the EBI.