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UniProt functional annotation for P12295 | ||
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| UniProt code: P12295. |
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| Organism: | |
Escherichia coli (strain K12). |
| Taxonomy: | |
Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales; Enterobacteriaceae; Escherichia. |
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| Function: | |
Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine. |
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| Catalytic activity: | |
Reaction=Hydrolyzes single-stranded DNA or mismatched double-stranded DNA and polynucleotides, releasing free uracil.; EC=3.2.2.27; |
| Subunit: | |
Monomer. |
| Subcellular location: | |
Cytoplasm. |
| Similarity: | |
Belongs to the uracil-DNA glycosylase (UDG) superfamily. UNG family. {ECO:0000305}. |
Annotations taken from UniProtKB at the EBI.