|
|
||
|
|
|
|
|
UniProt functional annotation for P00175 | ||
|
|
|
|
|
|
||
| UniProt code: P00175. |
|
||
| Organism: | |
Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast). |
| Taxonomy: | |
Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes; Saccharomycetales; Saccharomycetaceae; Saccharomyces. |
|
||
| Catalytic activity: | |
Reaction=(S)-lactate + 2 [Fe(III)cytochrome c] = 2 [Fe(II)cytochrome c] + 2 H(+) + pyruvate; Xref=Rhea:RHEA:19909, Rhea:RHEA-COMP:10350, Rhea:RHEA-COMP:14399, ChEBI:CHEBI:15361, ChEBI:CHEBI:15378, ChEBI:CHEBI:16651, ChEBI:CHEBI:29033, ChEBI:CHEBI:29034; EC=1.1.2.3; |
| Cofactor: | |
Name=FMN; Xref=ChEBI:CHEBI:58210; Evidence={ECO:0000269|PubMed:11914072}; |
| Cofactor: | |
Name=heme b; Xref=ChEBI:CHEBI:60344; Evidence={ECO:0000269|PubMed:11914072}; Note=Binds 1 heme b (iron(II)-protoporphyrin IX) group non-covalently per subunit. {ECO:0000269|PubMed:11914072}; |
| Subunit: | |
Homotetramer. |
| Subcellular location: | |
Mitochondrion intermembrane space {ECO:0000269|PubMed:11502169, ECO:0000269|PubMed:22984289}. |
| Induction: | |
By L-lactate. Induced during respiratory adaptation. |
| Miscellaneous: | |
Present with 4590 molecules/cell in log phase SD medium. {ECO:0000269|PubMed:14562106}. |
Annotations taken from UniProtKB at the EBI.