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UniProt functional annotation for Q5ZMW5 | ||
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| UniProt code: Q5ZMW5. |
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| Organism: | |
Gallus gallus (Chicken). |
| Taxonomy: | |
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda; Coelurosauria; Aves; Neognathae; Galloanserae; Galliformes; Phasianidae; Phasianinae; Gallus. |
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| Function: | |
GTPase-activating protein for RHOA and CDC42. {ECO:0000269|PubMed:10982819, ECO:0000269|PubMed:8649427}. |
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| Subunit: | |
Binds to the C-terminus of PTK2/FAK1. |
| Subcellular location: | |
Cell junction, focal adhesion {ECO:0000269|PubMed:8649427}. Cytoplasm, cytoskeleton {ECO:0000269|PubMed:8649427}. Note=Colocalizes with actin stress fibers and cortical actin structures. |
| Tissue specificity: | |
Detected in embryonic brain and liver, and at low levels in embryonic eye, heart, lung, intestine and skeletal muscle. {ECO:0000269|PubMed:8649427}. |
| Sequence caution: | |
Sequence=AAB07998.1; Type=Erroneous initiation; Evidence={ECO:0000305}; |
Annotations taken from UniProtKB at the EBI.