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UniProt functional annotation for P16932 | ||
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| UniProt code: P16932. |
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| Organism: | |
Burkholderia cepacia (Pseudomonas cepacia). |
| Taxonomy: | |
Bacteria; Proteobacteria; Betaproteobacteria; Burkholderiales; Burkholderiaceae; Burkholderia; Burkholderia cepacia complex. |
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| Function: | |
The dialkylglycine decarboxylase is of interest because it normally catalyzes both decarboxylation and amino transfer. It may be more properly described as a decarboxylating aminotransferase rather than an aminotransferring decarboxylase. |
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| Catalytic activity: | |
Reaction=2,2-dialkylglycine + H(+) + pyruvate = CO2 + dialkyl ketone + L-alanine; Xref=Rhea:RHEA:16073, ChEBI:CHEBI:15361, ChEBI:CHEBI:15378, ChEBI:CHEBI:16526, ChEBI:CHEBI:18044, ChEBI:CHEBI:57689, ChEBI:CHEBI:57972; EC=4.1.1.64; |
| Cofactor: | |
Name=pyridoxal 5'-phosphate; Xref=ChEBI:CHEBI:597326; |
| Subunit: | |
Homotetramer. |
| Miscellaneous: | |
The enzyme may have evolved to use the rare dialkylglycines of cosmic origin, or it may be part of a metabolic pathway for breaking down cytotoxic peptides and the constituent amino acids. |
| Similarity: | |
Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. {ECO:0000305}. |
Annotations taken from UniProtKB at the EBI.