UniProt functional annotation for P02904



	UniProt functional annotation for P02904

UniProt code: P02904.

Organism: Propionibacterium freudenreichii subsp. shermanii.

Taxonomy: Bacteria; Actinobacteria; Propionibacteriales; Propionibacteriaceae; Propionibacterium.

Function: The biotinyl 1.3S subunit serves as a carboxyl carrier between the substrate-binding sites on the 12S and 5S subunits.

Catalytic activity: Reaction=(S)-methylmalonyl-CoA + pyruvate = oxaloacetate + propanoyl- CoA; Xref=Rhea:RHEA:20764, ChEBI:CHEBI:15361, ChEBI:CHEBI:16452, ChEBI:CHEBI:57327, ChEBI:CHEBI:57392; EC=2.1.3.1;

Subunit: Transcarboxylase is composed of three subunits: 1.3S, 5S, and 12S. The core of the enzyme is composed of six 12S subunits. On each side of the core there are three pairs of 5S subunits. Each 5S dimer is attached to the core by two 1.3S subunits. Thus the total number of chains is 30 (6 + 12 + 12). {ECO:0000269|PubMed:1526981}.

Annotations taken from UniProtKB at the EBI.


Organism:		Propionibacterium freudenreichii subsp. shermanii.
Taxonomy:		Bacteria; Actinobacteria; Propionibacteriales; Propionibacteriaceae; Propionibacterium.



Function:		The biotinyl 1.3S subunit serves as a carboxyl carrier between the substrate-binding sites on the 12S and 5S subunits.


Catalytic activity:		Reaction=(S)-methylmalonyl-CoA + pyruvate = oxaloacetate + propanoyl- CoA; Xref=Rhea:RHEA:20764, ChEBI:CHEBI:15361, ChEBI:CHEBI:16452, ChEBI:CHEBI:57327, ChEBI:CHEBI:57392; EC=2.1.3.1;
Subunit:		Transcarboxylase is composed of three subunits: 1.3S, 5S, and 12S. The core of the enzyme is composed of six 12S subunits. On each side of the core there are three pairs of 5S subunits. Each 5S dimer is attached to the core by two 1.3S subunits. Thus the total number of chains is 30 (6 + 12 + 12). {ECO:0000269\|PubMed:1526981}.