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UniProt functional annotation for Q9X4D0 | ||
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| UniProt code: Q9X4D0. |
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| Organism: | |
Geobacillus stearothermophilus (Bacillus stearothermophilus). |
| Taxonomy: | |
Bacteria; Firmicutes; Bacilli; Bacillales; Bacillaceae; Geobacillus. |
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| Function: | |
RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication. {ECO:0000255|HAMAP-Rule:MF_00974}. |
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| Catalytic activity: | |
Reaction=SsDNA + n NTP = ssDNA/pppN(pN)(n-1) hybrid + (n-1) diphosphate.; EC=2.7.7.101; Evidence={ECO:0000255|HAMAP- Rule:MF_00974}; |
| Cofactor: | |
Name=Zn(2+); Xref=ChEBI:CHEBI:29105; Evidence={ECO:0000255|HAMAP-Rule:MF_00974, ECO:0000269|PubMed:10745010}; Note=Binds 1 zinc ion per monomer. {ECO:0000255|HAMAP-Rule:MF_00974, ECO:0000269|PubMed:10745010}; |
| Cofactor: | |
Name=Mg(2+); Xref=ChEBI:CHEBI:18420; Evidence={ECO:0000255|HAMAP-Rule:MF_00974}; Note=Binds two Mg(2+) per subunit. {ECO:0000255|HAMAP-Rule:MF_00974}; |
| Subunit: | |
Monomer (By similarity). Interacts with DnaB. {ECO:0000255|HAMAP-Rule:MF_00974, ECO:0000269|PubMed:10745010, ECO:0000269|PubMed:15837199, ECO:0000269|PubMed:17947583}. |
| Domain: | |
Contains an N-terminal zinc-binding domain, a central core domain that contains the primase activity, and a C-terminal DnaB- binding domain. {ECO:0000305|PubMed:10745010, ECO:0000305|PubMed:15837199, ECO:0000305|PubMed:17947583}. |
| Similarity: | |
Belongs to the DnaG primase family. {ECO:0000255|HAMAP- Rule:MF_00974}. |
Annotations taken from UniProtKB at the EBI.