UniProt functional annotation for P06716

UniProt code: P06716.

Organism: Escherichia coli.
Taxonomy: Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales; Enterobacteriaceae; Escherichia.
 
Function: This colicin is a channel-forming colicin. This class of transmembrane toxins depolarize the cytoplasmic membrane, leading to dissipation of cellular energy.
 
Function: Colicins are polypeptide toxins produced by and active against E.coli and closely related bacteria.
 
Subcellular location: Cell membrane {ECO:0000305}; Multi-pass membrane protein {ECO:0000305}.
Similarity: Belongs to the channel forming colicin family. {ECO:0000305}.

Annotations taken from UniProtKB at the EBI.