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PDBsum entry 1bbt
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Contents |
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186 a.a.
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210 a.a.
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220 a.a.
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46 a.a.
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* Residue conservation analysis
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References listed in PDB file
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Key reference
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Title
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Methods used in the structure determination of foot-And-Mouth disease virus.
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Authors
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E.Fry,
R.Acharya,
D.Stuart.
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Ref.
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Acta Crystallogr A, 1993,
49,
45-55.
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PubMed id
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Note In the PDB file this reference is
annotated as "TO BE PUBLISHED".
The citation details given above were identified by an automated
search of PubMed on title and author
names, giving a
percentage match of
81%.
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Abstract
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The structure of foot-and-mouth disease virus (FMDV) strain O1 BFS 1860 has been
determined to 2.9 A resolution using the molecular-replacement method [Acharya,
Fry, Stuart, Fox, Rowlands & Brown (1989). Nature (London), 337, 709-716].
Crystals of the virus with average dimensions 0.12 x 0.06 x 0.12 mm belong to
space group I23, a = 345 A with 1/12 of the icosahedral particle per asymmetric
unit giving fivefold noncrystallographic redundancy. Oscillation diffraction
photographs were collected at the SERC Synchrotron Radiation Source at Daresbury
in accordance with strict disease security regulations. The ambiguity in
particle orientation was resolved using a self-rotation function and starting
estimates of the phases to 8 A were derived from the known structures of two
picornaviruses similarly oriented in the I23 unit cell. The phases were refined
and extended using iterative averaging and solvent flattening with the
implementation of a simple automatic envelope-determination procedure to
increase the phasing power available.
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Secondary reference #1
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Title
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The three-Dimensional structure of foot-And-Mouth disease virus
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Authors
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R.Acharya,
E.Fry,
D.Logan,
D.Stuart,
F.Brown,
G.Fox,
D.Rowlands.
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Ref.
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new aspects of ...
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Secondary reference #2
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Title
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Architecture and topography of an aphthovirus
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Authors
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E.Fry,
D.Logan,
R.Acharya,
G.Fox,
D.Rowlands,
F.Brown,
D.Stuart.
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Ref.
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semin virol, 1990,
1,
439.
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Secondary reference #3
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Title
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Structural and serological evidence for a novel mechanism of antigenic variation in foot-And-Mouth disease virus.
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Authors
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N.Parry,
G.Fox,
D.Rowlands,
F.Brown,
E.Fry,
R.Acharya,
D.Logan,
D.Stuart.
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Ref.
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Nature, 1990,
347,
569-572.
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PubMed id
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Secondary reference #4
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Title
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Structure of foot-And-Mouth disease virus
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Authors
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R.Acharya,
E.Fry,
D.Logan,
D.I.Stuart,
G.Fox,
D.Rowlands,
F.Brown.
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Ref.
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use of x-ray crystallography ...
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Secondary reference #5
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Title
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The structure of foot-And-Mouth disease virus: implications for its physical and biological properties.
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Authors
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R.Acharya,
E.Fry,
D.Stuart,
G.Fox,
D.Rowlands,
F.Brown.
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Ref.
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Vet Microbiol, 1990,
23,
21-34.
[DOI no: ]
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PubMed id
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Secondary reference #6
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Title
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The three-Dimensional structure of foot-And-Mouth disease virus at 2.9 a resolution.
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Authors
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R.Acharya,
E.Fry,
D.Stuart,
G.Fox,
D.Rowlands,
F.Brown.
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Ref.
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Nature, 1989,
337,
709-716.
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PubMed id
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Secondary reference #7
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Title
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Implications of the three-Dimensional structure of foot-And-Mouth disease virus for its antigenicity and cell attachment
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Authors
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R.Acharya,
E.Fry,
D.Stuart,
G.Fox,
D.Rowlands,
F.Brown.
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Ref.
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vaccines 89: modern ...
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Secondary reference #8
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Title
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Crystallization and preliminary X-Ray diffraction analysis of foot-And-Mouth disease virus.
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Authors
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G.Fox,
D.Stuart,
K.R.Acharya,
E.Fry,
D.Rowlands,
F.Brown.
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Ref.
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J Mol Biol, 1987,
196,
591-597.
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PubMed id
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