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UniProt functional annotation for P48781 | ||
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| UniProt code: P48781. |
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| Organism: | |
Methanothermus fervidus. |
| Taxonomy: | |
Archaea; Euryarchaeota; Methanomada group; Methanobacteria; Methanobacteriales; Methanothermaceae; Methanothermus. |
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| Function: | |
Binds and compacts DNA (95 to 150 base pairs) to form nucleosome-like structures that contain positive DNA supercoils. Increases the resistance of DNA to thermal denaturation. {ECO:0000269|PubMed:2377617, ECO:0000269|PubMed:7809089}. |
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| Subunit: | |
Homodimer and heterodimer of HmfA and HmfB (PubMed:2377617, PubMed:7809089, PubMed:11021968). Forms primarily homodimers during exponential phase, and heterodimers appear when cells enter stationary phase (PubMed:7809089). Dimers then assemble into higher oligomers, with the DNA wrapped around the protein core (By similarity). {ECO:0000250|UniProtKB:P19267, ECO:0000269|PubMed:11021968, ECO:0000269|PubMed:2377617, ECO:0000269|PubMed:7809089}. |
| Subcellular location: | |
Cytoplasm {ECO:0000305|PubMed:2377617}. Chromosome {ECO:0000305|PubMed:2377617, ECO:0000305|PubMed:7809089}. |
| Induction: | |
Expressed at constant, high levels during exponential growth and during stationary phase. {ECO:0000269|PubMed:7809089}. |
| Similarity: | |
Belongs to the archaeal histone HMF family. {ECO:0000305}. |
Annotations taken from UniProtKB at the EBI.