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UniProt functional annotation for P55859 | ||
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| UniProt code: P55859. |
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| Organism: | |
Bos taurus (Bovine). |
| Taxonomy: | |
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Artiodactyla; Ruminantia; Pecora; Bovidae; Bovinae; Bos. |
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| Function: | |
Catalyzes the phosphorolytic breakdown of the N-glycosidic bond in the beta-(deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate (By similarity). Preferentially acts on 6-oxopurine nucleosides including inosine and guanosine (By similarity). {ECO:0000250|UniProtKB:P00491}. |
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| Catalytic activity: | |
Reaction=inosine + phosphate = alpha-D-ribose 1-phosphate + hypoxanthine; Xref=Rhea:RHEA:27646, ChEBI:CHEBI:17368, ChEBI:CHEBI:17596, ChEBI:CHEBI:43474, ChEBI:CHEBI:57720; EC=2.4.2.1; Evidence={ECO:0000250|UniProtKB:P00491}; |
| Catalytic activity: | |
Reaction=guanosine + phosphate = alpha-D-ribose 1-phosphate + guanine; Xref=Rhea:RHEA:13233, ChEBI:CHEBI:16235, ChEBI:CHEBI:16750, ChEBI:CHEBI:43474, ChEBI:CHEBI:57720; EC=2.4.2.1; Evidence={ECO:0000250|UniProtKB:P00491}; |
| Catalytic activity: | |
Reaction=2'-deoxyguanosine + phosphate = 2-deoxy-alpha-D-ribose 1- phosphate + guanine; Xref=Rhea:RHEA:27738, ChEBI:CHEBI:16235, ChEBI:CHEBI:17172, ChEBI:CHEBI:43474, ChEBI:CHEBI:57259; EC=2.4.2.1; Evidence={ECO:0000250|UniProtKB:P23492}; |
| Catalytic activity: | |
Reaction=2'-deoxyinosine + phosphate = 2-deoxy-alpha-D-ribose 1- phosphate + hypoxanthine; Xref=Rhea:RHEA:27750, ChEBI:CHEBI:17368, ChEBI:CHEBI:28997, ChEBI:CHEBI:43474, ChEBI:CHEBI:57259; EC=2.4.2.1; Evidence={ECO:0000250|UniProtKB:P23492}; |
| Pathway: | |
Purine metabolism; purine nucleoside salvage. {ECO:0000250|UniProtKB:P00491}. |
| Subunit: | |
Homotrimer. {ECO:0000250|UniProtKB:P00491}. |
| Subcellular location: | |
Cytoplasm {ECO:0000250|UniProtKB:P00491}. |
| Similarity: | |
Belongs to the PNP/MTAP phosphorylase family. {ECO:0000305}. |
Annotations taken from UniProtKB at the EBI.