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UniProt functional annotation for Q27450 | ||
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| UniProt code: Q27450. |
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| Organism: | |
Brugia malayi (Filarial nematode worm). |
| Taxonomy: | |
Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Spirurina; Spiruromorpha; Filarioidea; Onchocercidae; Brugia. |
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| Function: | |
PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides. |
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| Catalytic activity: | |
Reaction=[protein]-peptidylproline (omega=180) = [protein]- peptidylproline (omega=0); Xref=Rhea:RHEA:16237, Rhea:RHEA- COMP:10747, Rhea:RHEA-COMP:10748, ChEBI:CHEBI:83833, ChEBI:CHEBI:83834; EC=5.2.1.8; |
| Activity regulation: | |
Relatively insensitive to inhibition by cyclosporin A (CsA). |
Annotations taken from UniProtKB at the EBI.