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UniProt functional annotation for P27616 | ||
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| UniProt code: P27616. |
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| Organism: | |
Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast). |
| Taxonomy: | |
Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes; Saccharomycetales; Saccharomycetaceae; Saccharomyces. |
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| Catalytic activity: | |
Reaction=5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxylate + ATP + L-aspartate = (2S)-2-[5-amino-1-(5-phospho-beta-D-ribosyl)imidazole- 4-carboxamido]succinate + ADP + 2 H(+) + phosphate; Xref=Rhea:RHEA:22628, ChEBI:CHEBI:15378, ChEBI:CHEBI:29991, ChEBI:CHEBI:30616, ChEBI:CHEBI:43474, ChEBI:CHEBI:58443, ChEBI:CHEBI:77657, ChEBI:CHEBI:456216; EC=6.3.2.6; |
| Pathway: | |
Purine metabolism; IMP biosynthesis via de novo pathway; 5- amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxamide from 5-amino-1-(5- phospho-D-ribosyl)imidazole-4-carboxylate: step 1/2. |
| Subunit: | |
Monomer. |
| Miscellaneous: | |
Present with 4280 molecules/cell in log phase SD medium. {ECO:0000269|PubMed:14562106}. |
| Similarity: | |
Belongs to the SAICAR synthetase family. {ECO:0000305}. |
Annotations taken from UniProtKB at the EBI.