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PDBsum entry 1a0t
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Outer membrane protein
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PDB id
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1a0t
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References listed in PDB file
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Key reference
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Title
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Structure of the sucrose-Specific porin scry from salmonella typhimurium and its complex with sucrose.
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Authors
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D.Forst,
W.Welte,
T.Wacker,
K.Diederichs.
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Ref.
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Nat Struct Biol, 1998,
5,
37-46.
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PubMed id
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Abstract
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The X-ray structure of a sucrose-specific porin (ScrY) from Salmonella
typhimurium has been determined by multiple isomorphous replacement at 2.4 A
resolution both in its uncomplexed form and with bound sucrose. ScrY is a
noncrystallographic trimer of identical subunits, each with 413 structurally
well-defined amino acids. A monomer is built up of 18 anti-parallel beta-strands
surrounding a hydrophilic pore, with a topology closely similar to that of
maltoporin. Two non-overlapping sucrose-binding sites were identified in
difference Fourier maps. The higher permeability for sucrose of ScrY as compared
to maltoporin is mainly accounted for by differences in their pore-lining
residues.
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Secondary reference #1
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Title
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Crystallization and preliminary X-Ray diffraction analysis of scry, A specific bacterial outer membrane porin.
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Authors
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D.Forst,
K.Schülein,
T.Wacker,
K.Diederichs,
W.Kreutz,
R.Benz,
W.Welte.
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Ref.
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J Mol Biol, 1993,
229,
258-262.
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PubMed id
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