UniProt functional annotation for P19632

UniProt code: P19632.

Organism: Bos taurus (Bovine).
Taxonomy: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Artiodactyla; Ruminantia; Pecora; Bovidae; Bovinae; Bos.
 
Function: Inhibits the transcriptional activation activity of the cone- rod homeobox CRX (By similarity). May participate in the regulation of visual phototransduction or in the integration of photoreceptor metabolism. {ECO:0000250}.
 
Subunit: Interacts with CRX (By similarity). Forms a complex with the beta and gamma subunits of the GTP-binding protein, transducin. {ECO:0000250}.
Subcellular location: Cytoplasm, cytosol {ECO:0000250|UniProtKB:P20941}. Nucleus {ECO:0000250|UniProtKB:P20941}. Cell projection, cilium, photoreceptor outer segment {ECO:0000269|PubMed:10866677}. Photoreceptor inner segment {ECO:0000269|PubMed:10866677}.
Ptm: Light-induced changes in cyclic nucleotide levels modulate the phosphorylation of this protein by cAMP kinase. {ECO:0000250}.
Similarity: Belongs to the phosducin family. {ECO:0000305}.
Sequence caution: Sequence=AAA62716.1; Type=Frameshift; Evidence={ECO:0000305};

Annotations taken from UniProtKB at the EBI.