Ligand clusters for UniProt code Q12051

Ligand clusters for Q12051: Geranylgeranyl pyrophosphate synthase from Saccharomyces cerevisiae (strain ATCC 204508 / S288c)

		2 ligand clusters Cluster 1. 22 ligand types 65 ligands Cluster 2. 3 ligand types 5 ligands
Representative protein: 2dh4A

Structures

PDB		Schematic diagram
2dh4A
2z78A
2e8xB
2e8wA
2e95A
		more ...

Cluster 1 contains 22 ligand types (of which only 20 are listed. Click for all)

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Ligand		Description
		1. Ligand: IPE × 4 3-Methylbut-3-Enyl trihydrogen diphosphate PDB codes: 2e8t(A), 2e8u(A), 2e8w(A).
		2. Ligand: GPP × 2 Geranyl diphosphate PDB codes: 2e8x(A),
		3. Ligand: GRG × 1 Geranylgeranyl diphosphate PDB code: 2e8v(A).
		4. Ligand: FPP × 1 Farnesyl diphosphate PDB code: 2e90(A).
_Mg		5. Metal: _MG × 34 PDB codes: 2dh4(A), 2e8t(A), 2e8u(A), 2e8w(A), 2e8x(A), 2e90(A), 2e91(A), 2e92(A), 2e94(A), 2e95(A), 2z4v(A), 2z4w(A), 2z4x(A), 2z4z(A), 2z52(A), 2z7h(A), 2z7i(A), 2zev(A),
		6. Ligand: PPV × 1 pyrophosphoric acid Pyrophosphate PDB code: 2e90(A).
		7. Ligand: ZOL × 1 zoledronic acid Zoledronic acid PDB code: 2e91(A).
		8. Ligand: FPS × 1 S-[(2e,6e)-3,7,11-Trimethyldodeca-2,6,10-Trienyl] trihydrogen thiodiphosphate PDB code: 2e8t(A).
		9. Ligand: M0N × 1 (1-Hydroxy-2-Imidazo[1,2-A]pyridin-3-Ylethane-1,1- Diyl)bis(phosphonic acid) PDB code: 2e92(A).
		10. Ligand: 364 × 1 3-Biphenyl-3-Yl-1-(2-Hydroxy-2,2-Diphosphonoethyl) pyridinium PDB code: 2e94(A).
		11. Ligand: B29 × 4 [2-(3-Dibenzofuran-4-Yl-Phenyl)-1-Hydroxy-1-Phosphono- Ethyl]-Phosphonic acid PDB codes: 2e93(A),
		12. Ligand: B75 × 1 1-Hydroxy-2-[3'-(Naphthalene-2-Sulfonylamino)- Biphenyl-3-Yl]ethylidene-1,1-Bisphosphonic acid PDB code: 2e95(A).
		13. Ligand: 252 × 3 (1-Hydroxynonane-1,1-Diyl)bis(phosphonic acid) PDB codes: 2z4x(A), 2z4y(A),
		14. Ligand: B71 × 2 3-(Decyloxy)-1-(2,2-Diphosphonoethyl)pyridinium PDB codes: 2zeu(A), 2zev(A).
		15. Ligand: GRG × 1 Geranylgeranyl diphosphate PDB code: 2z4v(A).
		16. Ligand: 028 × 1 (1-Hydroxyheptane-1,1-Diyl)bis(phosphonic acid) PDB code: 2z50(A).
		17. Ligand: 742 × 1 (2,2-Diphosphonoethyl)(dodecyl)dimethylphosphonium PDB code: 2z7i(A).
		18. Ligand: 749 × 1 [(6e,11e)-2,6,12,16-Tetramethylheptadeca-2,6,11,15- Tetraene-9,9-Diyl]bis(phosphonic acid) PDB code: 2z4w(A).
		19. Ligand: GG3 × 1 {1-Hydroxy-3-[Methyl(4-Phenylbutyl)amino]propane-1,1- Diyl}bis(phosphonic acid) PDB code: 2z7h(A).
		20. Ligand: H23 × 1 (1-Hydroxydodecane-1,1-Diyl)bis(phosphonic acid) PDB code: 2z52(A).
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Cluster 2 contains 3 ligand types

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Ligand		Description
		1. Ligand: GPP × 2 Geranyl diphosphate PDB codes: 2e8x(A),
		2. Ligand: 252 × 2 (1-Hydroxynonane-1,1-Diyl)bis(phosphonic acid) PDB codes: 2z4x(A), 2z4y(A).
		3. Ligand: 749 × 1 [(6e,11e)-2,6,12,16-Tetramethylheptadeca-2,6,11,15- Tetraene-9,9-Diyl]bis(phosphonic acid) PDB code: 2z4w(A).