Ligand clusters for UniProt code P56273

Ligand clusters for P56273: E3 ubiquitin-protein ligase Mdm2 from Xenopus laevis

		6 ligand clusters Cluster 1. 12 ligand types 13 ligands Cluster 2. 1 ligand type 6 ligands Cluster 3. 1 ligand type 1 ligand Cluster 4. 1 ligand type 2 ligands Cluster 5. 1 ligand type 1 ligand Cluster 6. 1 ligand type 1 ligand
Representative protein: 1ttvA

Structures

PDB		Schematic diagram
1ttvA
4j74A
4j7dA
4j7eA
4jrgA
		more ...

Cluster 1 contains 12 ligand types

Use checkboxes to select ligands to display in RasMol, Jmol, or download as an SDF file. Selection shortcuts: select all/none invert selection.
Ligand		Description
		1. Ligand: I18 × 2 (4s,5r)-4,5-Bis(4-Chlorophenyl)-2-Methyl-4,5-Dihydro- 1h-Imidazole PDB codes: 4j74(A),
		2. Ligand: 1F0 × 1 [(4s,5r)-2-(4-Tert-Butyl-2-Ethoxyphenyl)-4,5-Bis(4- Chlorophenyl)-4,5-Dimethyl-4,5-Dihydro-1h- Imidazol-1- Yl]{4-[3-(Methylsulfonyl)propyl]piperazin-1- Yl}methanone PDB code: 4ipf(A).
		3. Ligand: 1OY × 1 (3s,4r,5s)-3-(3-Chloro-2-Fluorophenyl)-4-(4-Chloro-2- Fluorophenyl)-4-Cyano-N-[(3s)-3,4- Dihydroxybutyl]-5- (2,2-Dimethylpropyl)-D-Prolinamide PDB code: 4jsc(A).
		4. Ligand: 20Q × 1 (3s)-3-[(3r)-1-Acetylpiperidin-3-Yl]-6-Chloro-3-(3- Chlorobenzyl)-1,3-Dihydro-2h-Indol-2-One PDB code: 4lwt(A).
		5. Ligand: 20U × 1 (2'S,3r,4'S,5'R)-N-(4-Carbamoylphenyl)-6-Chloro-4'-(3- Chloro-2-Fluorophenyl)-2'-(2,2- Dimethylpropyl)-2-Oxo- 1,2-Dihydrospiro[indole-3,3'-Pyrrolidine]-5'- Carboxamide PDB code: 4lwu(A).
		6. Ligand: 20W × 1 (2s,3r,4r,5r)-N-(4-Carbamoyl-2-Methoxyphenyl)-2'- Chloro-4-(3-Chloro-2-Fluorophenyl)-2-(2,2- Dimethylpropyl)-5'-Oxo-4',5'-Dihydrospiro[pyrrolidine- 3,6'-Thieno[3,2-B]pyrrole]-5-Carboxamide PDB code: 4lwv(A).
		7. Ligand: I09 × 1 (3r,4r,5s)-3-(3-Chlorophenyl)-4-(4-Chlorophenyl)-4- Cyano-N-[(3s)-3,4-Dihydroxybutyl]-5-(2,2- Dimethylpropyl)-D-Prolinamide PDB code: 4jrg(A).
		8. Ligand: I29 × 1 [(4s,5r)-4,5-Bis(4-Chlorophenyl)-2,4,5-Trimethyl-4,5- Dihydro-1h-Imidazol-1-Yl]{4-[3- (Methylsulfonyl) propyl]piperazin-1-Yl}methanone PDB code: 4j7e(A).
		9. Ligand: I31 × 1 (4s,5r)-2-(4-Tert-Butyl-2-Ethoxyphenyl)-4,5-Bis(4- Chlorophenyl)-4,5-Dimethyl-4,5-Dihydro-1h- Imidazole PDB code: 4j7d(A).
		10. Ligand: IMY × 1 1-{[4,5-Bis(4-Chlorophenyl)-2-(2-Isopropoxy-4- Methoxyphenyl)-4,5-Dihydro-1h-Imidazol-1- Yl]carbonyl}piperazine PDB code: 1ttv(A).
		11. Ligand: NUT × 1 4-({(4s,5r)-4,5-Bis(4-Chlorophenyl)-2-[4-Methoxy-2- (Propan-2-Yloxy)phenyl]-4,5-Dihydro-1h- Imidazol-1- Yl}carbonyl)piperazin-2-One PDB code: 4j3e(A).
		12. Ligand: SO4 × 1 Sulfate ion PDB code: 4lwu(A).

Cluster 2 contains 1 ligand type

Selection shortcuts: select all/none invert selection.
Ligand		Description
		1. Ligand: SO4 × 6 Sulfate ion PDB codes: 4ipf(A), 4j3e(A), 4j74(A), 4j7e(A), 4lwt(A), 4lwv(A).

Cluster 3 contains 1 ligand type

Selection shortcuts: select all/none invert selection.
Ligand		Description
		1. Ligand: SO4 × 1 Sulfate ion PDB code: 4ipf(A).

Cluster 4 contains 1 ligand type

Selection shortcuts: select all/none invert selection.
Ligand		Description
		1. Ligand: SO4 × 2 Sulfate ion PDB codes: 4j7d(A), 4lwv(A).

Cluster 5 contains 1 ligand type

Selection shortcuts: select all/none invert selection.
Ligand		Description
		1. Ligand: SO4 × 1 Sulfate ion PDB code: 4j7d(A).

Cluster 6 contains 1 ligand type

Selection shortcuts: select all/none invert selection.
Ligand		Description
		1. Ligand: SO4 × 1 Sulfate ion PDB code: 4lwv(A).