Ligand clusters for UniProt code P22681

Ligand clusters for P22681: E3 ubiquitin-protein ligase CBL from Homo sapiens

		Top 6 (of 21) ligand clusters Cluster 1. 11 ligand types 15 ligands Cluster 2. 1 ligand type 1 ligand Cluster 3. 1 ligand type 1 ligand Cluster 4. 1 ligand type 1 ligand Cluster 5. 1 ligand type 1 ligand Cluster 6. 1 ligand type 1 ligand
Representative protein: 1fbvA

Structures

PDB		Schematic diagram
1fbvA
4a4bA
4a4cA
3buxB
3bunB
		more ...

Cluster 1 contains 11 ligand types

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Ligand		Description
		1. Ligand: SER-ASP-GLY-PTR-THR-PRO-GLU-PRO-ALA × 5 PTR=O-Phosphotyrosine. PDB codes: 1fbv(A), 2cbl(A), 2y1n(A), 4a4b(A), 4a4c(A).
		2. Ligand: ACE-GLU-PTR-THR-GLU-GLY-PRO × 1 ACE=Acetyl group, PTR=O-Phosphotyrosine. PDB code: 5hl0(A).
		3. Ligand: ACE-PTR-THR-PRO-GLU-PRO-NH2 × 1 ACE=Acetyl group, PTR=O-Phosphotyrosine, NH2=Amino group. PDB code: 4gpl(B).
		4. Ligand: ARG-ALA-VAL-GLU-ASN-GLN-PTR-SER-PHE × 1 PTR=O-Phosphotyrosine. PDB code: 1yvh(A).
		5. Ligand: ARG-ASN-THR-ASN-GLU-PTR-TPO-GLU-GLY-PRO × 1 PTR=O-Phosphotyrosine, TPO=Phosphothreonine. PDB code: 3ob1(B).
		6. Ligand: ARG-PTR-ASP-ALA × 1 PTR=O-Phosphotyrosine. PDB code: 3plf(B).
		7. Ligand: ASN-ASP-PTR-ILE-ASP-ASN-PRO × 1 PTR=O-Phosphotyrosine. PDB code: 3bun(B).
		8. Ligand: ASN-GLU-SER-VAL-ASP-PTR-ARG-ALA × 1 PTR=O-Phosphotyrosine. PDB code: 3bux(B).
		9. Ligand: ASP-GLY-PTR-THR-PRO-GLU-PRO × 1 PTR=O-Phosphotyrosine. PDB code: 5o76(A).
		10. Ligand: SER-PHE-ASN-PRO-PTR-GLU-PRO-GLU-LEU × 1 PTR=O-Phosphotyrosine. PDB code: 3buw(B).
		11. Ligand: THR-ASN-GLU-PTR-THR-GLU-GLY-PRO-THR × 1 PTR=O-Phosphotyrosine. PDB code: 3bum(B).

Cluster 2 contains 1 ligand type

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Ligand		Description
		1. Ligand: 1PE × 1 Pentaethylene glycol PDB code: 5hky(A).

Cluster 3 contains 1 ligand type

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Ligand		Description
		1. Ligand: SO4 × 1 Sulfate ion PDB code: 1fbv(A).

Cluster 4 contains 1 ligand type

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Ligand		Description
		1. Ligand: SO4 × 1 Sulfate ion PDB code: 1fbv(A).

Cluster 5 contains 1 ligand type

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Ligand		Description
		1. Ligand: SO4 × 1 Sulfate ion PDB code: 1fbv(A).

Cluster 6 contains 1 ligand type

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Ligand		Description
		1. Ligand: SO4 × 1 Sulfate ion PDB code: 1fbv(A).