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Ligand clusters for UniProt code P20292
Ligand clusters for P20292: Arachidonate 5-lipoxygenase-activating protein from Homo sapiens
4 ligand clusters
Cluster 1.
4 ligand types
11 ligands
Cluster 2.
4 ligand types
11 ligands
Cluster 3.
1 ligand type
1 ligand
Cluster 4.
1 ligand type
3 ligands
Representative protein: 6vgcD
Structures
PDB
Schematic diagram
6vgc
D
6vgi
F
6vgi
D
6vgc
B
6vgi
C
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Cluster 1 contains 4 ligand types
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Ligand
Description
1. Ligand:
QY7 × 4
3-[3-(Tert-Butylsulfanyl)-1-[(4-Chlorophenyl)methyl]-5- (Propan-2-Yl)-1h-Indol-2-Yl]-2,2-
Dimethylpropanoic acid
PDB codes:
6vgi
(A),
2. Ligand:
QY1 × 3
(2r)-Cyclopentyl{4-[(Quinolin-2-Yl) methoxy]phenyl}acetic acid
PDB codes:
6vgc
(A),
3. Ligand:
2CS × 2
3-[3-(Tert-Butylthio)-1-(4-Chlorobenzyl)-5-(Quinolin- 2-Ylmethoxy)-1h-Indol-2-Yl]-2,2-
Dimethylpropanoic acid
PDB codes:
2q7m
(A),
4. Ligand:
3CS × 2
3-[3-(3,3-Dimethylbutanoyl)-1-(4-Iodobenzyl)-5- (Quinolin-2-Ylmethoxy)-1h-Indol-2-Yl]-2,2-
Dimethylpropanoic acid
PDB codes:
2q7r
(A),
Cluster 2 contains 4 ligand types
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Ligand
Description
1. Ligand:
QY7 × 4
3-[3-(Tert-Butylsulfanyl)-1-[(4-Chlorophenyl)methyl]-5- (Propan-2-Yl)-1h-Indol-2-Yl]-2,2-
Dimethylpropanoic acid
PDB codes:
6vgi
(A),
2. Ligand:
QY1 × 3
(2r)-Cyclopentyl{4-[(Quinolin-2-Yl) methoxy]phenyl}acetic acid
PDB codes:
6vgc
(A),
3. Ligand:
2CS × 2
3-[3-(Tert-Butylthio)-1-(4-Chlorobenzyl)-5-(Quinolin- 2-Ylmethoxy)-1h-Indol-2-Yl]-2,2-
Dimethylpropanoic acid
PDB codes:
2q7m
(A),
4. Ligand:
3CS × 2
3-[3-(3,3-Dimethylbutanoyl)-1-(4-Iodobenzyl)-5- (Quinolin-2-Ylmethoxy)-1h-Indol-2-Yl]-2,2-
Dimethylpropanoic acid
PDB codes:
2q7r
(A),
Cluster 3 contains 1 ligand type
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Ligand
Description
1. Ligand:
BOG × 1
Octyl beta-D-Glucopyranoside
PDB code:
6vgc
(B).
Cluster 4 contains 1 ligand type
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Ligand
Description
1. Ligand:
SO4 × 3
Sulfate ion
PDB codes:
6vgi
(A),