Ligand clusters for UniProt code P14324

Ligand clusters for P14324: Farnesyl pyrophosphate synthase from Homo sapiens

		Top 6 (of 19) ligand clusters Cluster 1. 70 ligand types 339 ligands Cluster 2. 3 ligand types 3 ligands Cluster 3. 2 ligand types 2 ligands Cluster 4. 3 ligand types 4 ligands Cluster 5. 2 ligand types 11 ligands Cluster 6. 1 ligand type 3 ligands
Representative protein: 2f89F

Structures

PDB		Schematic diagram
2f89F
4ga3A
5cg6A
4pvyF
5cg5A
		more ...

Cluster 1 contains 70 ligand types (of which only 20 are listed. Click for all)

Use checkboxes to select ligands to display in RasMol, Jmol, or download as an SDF file. Selection shortcuts: select all/none invert selection.
Ligand		Description
		1. Ligand: IPE × 1 3-Methylbut-3-Enyl trihydrogen diphosphate PDB code: 2f8z(F).
_Mg		2. Metal: _MG × 143 PDB codes: 1yq7(A), 1yv5(A), 1zw5(A), 2f8c(F), 2f8z(F), 2opm(A), 2opn(A), 2qis(A), 2rah(A), 2vf6(A), 3cp6(A), 3n45(F), 3n46(F), 3rye(A), 3s4j(A), 4dem(F), 4ga3(A), 4h5c(F), 4h5d(F), 4h5e(F), 4jvj(F), 4kfa(A), 4kpd(A), 4kpj(A), 4kq5(A), 4kqs(A), 4kqu(A), 4l2x(F), 4lfv(F), 4n1z(F), 4n9u(A), 4nfi(F), 4nfj(F), 4ng6(A), 4nke(A), 4nkf(A), 4nua(A), 4ogu(A), 4p0v(A), 4p0w(A), 4pvx(F), 4pvy(F), 4q23(A), 4qpf(A), 4xqs(F), 4xqt(F), 5cg5(A), 5cg6(A), 5diq(F), 5ygi(A),
		3. Ligand: RIS × 12 risedronic acid 1-Hydroxy-2-(3-Pyridinyl)ethylidene bis-Phosphonic acid PDB codes: 1yq7(A), 1yv5(A), 2qis(A), 4kpd(A), 4kqs(A), 4n9u(A), 4ng6(A), 4nke(A), 4nua(A), 4q23(A), 5cg5(A), 5cg6(A).
		4. Ligand: ZOL × 10 zoledronic acid Zoledronic acid PDB codes: 1zw5(A), 2f8c(F), 2f8z(F), 2f9k(F), 3n45(F), 3n46(F), 4kfa(A), 4kq5(A), 4p0v(A), 4p0w(A).
_Zn		5. Metal: _ZN × 9 PDB codes: 2f92(F), 2f94(F), 2f9k(F),
		6. Ligand: 210 × 4 pamidronic acid Pamidronate PDB codes: 2f89(F), 4kpj(A), 4nkf(A), 4ogu(A).
_Mn		7. Metal: _MN × 3 PDB codes: 2f89(F),
		8. Ligand: BFQ × 1 ibandronate Ibandronate PDB code: 2f94(F).
		9. Ligand: GOL × 1 glycerin Glycerol PDB code: 5diq(F).
		10. Ligand: PO4 × 10 Phosphate ion PDB codes: 1yq7(A), 1yv5(A), 2f7m(F), 2f89(F), 2f8c(F), 2f92(F), 2f94(F), 2f9k(F).
		11. Ligand: AHD × 1 4-Amino-1-Hydroxybutane-1,1-Diyldiphosphonate PDB code: 2f92(F).
		12. Ligand: M0N × 2 (1-Hydroxy-2-Imidazo[1,2-A]pyridin-3-Ylethane-1,1- Diyl)bis(phosphonic acid) PDB codes: 2vf6(A), 3b7l(A).
		13. Ligand: PO4 × 42 Phosphate ion PDB codes: 2opm(A), 2opn(A), 3n1v(F), 3n1w(F), 3n3l(F), 3n45(F), 3n46(F), 3n49(F), 3n5h(F), 3n5j(F), 3n6k(F), 4ga3(A), 4h5c(F), 4lfv(F), 4lpg(F), 4lph(F), 4n1z(F), 4nua(A), 4qxs(F), 4rxa(A), 4xqr(F), 5dgm(F), 5diq(F), 5djp(F), 5djr(F), 5ja0(F), 5jv2(F), 5ksx(F), 5ygi(A), 6n7y(F), 6n82(F), 6n83(F), 6oag(F), 6oah(F).
		14. Ligand: SO4 × 12 Sulfate ion PDB codes: 2rah(A), 3rye(A), 3s4j(A), 4jvj(F), 4nfj(F), 4nfk(F), 4q23(A), 4xqs(F), 4xqt(F), 5jv0(F), 5jv1(F).
		15. Ligand: IPE × 8 3-Methylbut-3-Enyl trihydrogen diphosphate PDB codes: 1zw5(A), 4kpd(A), 4kqs(A), 4kqu(A), 4ng6(A), 4nke(A), 4ogu(A), 5cg6(A).
		16. Ligand: YS4 × 5 [({4-[4-(Propan-2-Yloxy)phenyl]pyridin-2-Yl}amino) methanediyl]bis(phosphonic acid) PDB codes: 4dem(F), 4h5c(F), 4h5d(F), 4h5e(F), 4lfv(F).
		17. Ligand: EDO × 4 1,2-Ethanediol PDB codes: 4kpj(A), 4nke(A), 4nua(A),
		18. Ligand: 1WO × 3 (5beta)-11-Hydroxyabieta-7,9(11),13-Triene-6,12-Dione PDB codes: 4p0v(A), 4p0x(A),
		19. Ligand: JD5 × 3 [({5-[4-(Cyclopropyloxy)phenyl]pyridin-3-Yl}amino) methanediyl]bis(phosphonic acid) PDB codes: 4nfi(F), 4nfj(F), 4nfk(F).
		20. Ligand: YL6 × 3 [(1r)-1-{[6-(3-Chloro-4-Methylphenyl)thieno[2,3- D]pyrimidin-4-Yl]amino}-2-(3- Fluorophenyl) ethyl]phosphonic acid PDB codes: 5jv1(F), 6n83(F).
+ more. Press for full list

Cluster 2 contains 3 ligand types

Selection shortcuts: select all/none invert selection.
Ligand		Description
		1. Ligand: EDO × 1 1,2-Ethanediol PDB code: 4kpj(A).
		2. Ligand: GO0 × 1 3-(Carboxymethyl)-4,7-Dichloro-1h-Indole-2-Carboxylic acid PDB code: 3n5h(F).
		3. Ligand: GO1 × 1 3-(Carboxymethyl)-5,7-Dichloro-1h-Indole-2-Carboxylic acid PDB code: 3n5j(F).

Cluster 3 contains 2 ligand types

Selection shortcuts: select all/none invert selection.
Ligand		Description
		1. Ligand: EDO × 1 1,2-Ethanediol PDB code: 4nua(A).
		2. Ligand: YL5 × 1 [(1r)-2-(3-Fluorophenyl)-1-{[6-(4-Methylphenyl) thieno[2,3-D]pyrimidin-4- Yl]amino}ethyl]phosphonic acid PDB code: 5jv0(F).

Cluster 4 contains 3 ligand types

Selection shortcuts: select all/none invert selection.
Ligand		Description
		1. Ligand: GOL × 1 glycerin Glycerol PDB code: 5djr(F).
		2. Ligand: EDO × 2 1,2-Ethanediol PDB codes: 4kfa(A), 4kq5(A).
		3. Ligand: PEG × 1 Di(hydroxyethyl)ether PDB code: 4nkf(A).

Cluster 5 contains 2 ligand types

Selection shortcuts: select all/none invert selection.
Ligand		Description
		1. Ligand: GOL × 9 glycerin Glycerol PDB codes: 4pvx(F), 4pvy(F), 4qxs(F), 5diq(F), 5djr(F), 6n7y(F), 6n7z(F), 6n82(F), 6oah(F).
		2. Ligand: EDO × 2 1,2-Ethanediol PDB codes: 4n9u(A), 4nua(A).

Cluster 6 contains 1 ligand type

Selection shortcuts: select all/none invert selection.
Ligand		Description
		1. Ligand: SO4 × 3 Sulfate ion PDB codes: 4xqs(F), 5jv0(F), 5jv1(F).