Ligand clusters for UniProt code P08514

Ligand clusters for P08514: Integrin alpha-IIb OS=Homo sapiens GN=ITGA2B PE=1 SV=3

		Top 6 (of 25) ligand clusters Cluster 1. 13 ligand types 19 ligands Cluster 2. 8 ligand types 21 ligands Cluster 3. 1 ligand type 1 ligand Cluster 4. 1 ligand type 1 ligand Cluster 5. 1 ligand type 1 ligand Cluster 6. 2 ligand types 3 ligands
Representative protein: 3fcsA

Structures

PDB		Schematic diagram
3fcsA
4cakA
6v4pA
2vdqA
3zdyA
		more ...

Cluster 1 contains 13 ligand types

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Ligand		Description
		1. Ligand: GOL × 2 glycerin Glycerol PDB codes: 3nid(A),
		2. Ligand: AGG × 1 tirofiban Tirofiban PDB code: 2vdm(A).
_Mg		3. Metal: _MG × 1 PDB code: 2vc2(A).
		4. Ligand: GLY-ARG-GLY-ASP-SER-PRO × 3 PDB codes: 3zdz(A), 3ze0(A), 3ze1(A).
		5. Ligand: ALA-GLY-ASP-VAL × 2 PDB codes: 4z7n(A), 4z7o(A).
		6. Ligand: ALA-LYS-GLN-ARG-GLY-ASP-VAL × 2 PDB codes: 2vdq(A), 2vdr(A).
		7. Ligand: GLY-ARG-GLY × 2 PDB codes: 3zdy(A), 3ze2(A).
		8. Ligand: 180 × 1 2-(S)-[N-(3-Pyridylsulfonyl)amino]-3-[[2-Carbonyl-5-[2- (Piperidin-4-Yl)ethyl]-Thieno[2,3- B]thiopheneyl]amino]-Propionic acid PDB code: 2vc2(A).
		9. Ligand: ALA-GLY-ASP-VAL-NH2 × 1 NH2=Amino group. PDB code: 4z7q(A).
		10. Ligand: GLY-ALA-LYS-GLN-ALA-GLY-ASP-VAL × 1 PDB code: 2vdp(A).
		11. Ligand: MPT-HRG-GLY-ASP-TRP-PRO-CYS-NH2 × 1 MPT=Beta-Mercaptopropionic acid, HRG=L-Homoarginine, NH2=Amino group. PDB code: 2vdn(A).
		12. Ligand: NIF × 1 2-Ethyl-7-Piperazin-1-Yl-5h-[1,3,4]thiadiazolo[3,2- A]pyrimidin-5-One PDB code: 3nif(A).
		13. Ligand: RC2 × 1 N-{3-[5-Oxo-7-(Piperazin-1-Yl)-5h-[1,3,4]thiadiazolo[3, 2-A]pyrimidin-2-Yl]phenyl}glycinamide PDB code: 3t3m(A).

Cluster 2 contains 8 ligand types

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Ligand		Description
		1. Ligand: GOL × 1 glycerin Glycerol PDB code: 3nif(A).
		2. Ligand: NAG-NAG-MAN-MAN-MAN × 11 NAG=N-Acetyl-D-Glucosamine, MAN=Alpha-D-Mannose. PDB codes: 2vc2(A), 2vdk(A), 2vdl(A), 2vdm(A), 2vdn(A), 2vdo(A), 2vdp(A), 2vdq(A), 2vdr(A), 3fcu(A), 3nid(A).
		3. Ligand: NAG-NAG-BMA-MAN-MAN × 2 NAG=N-Acetyl-D-Glucosamine, BMA=Beta-D-Mannose, MAN=Alpha-D-Mannose. PDB codes: 3t3m(A), 3t3p(A).
		4. Ligand: NAG-NAG-MAN-MAN × 2 NAG=N-Acetyl-D-Glucosamine, MAN=Alpha-D-Mannose. PDB codes: 3fcs(A), 3nif(A).
		5. Ligand: SO4 × 2 Sulfate ion PDB codes: 3nif(A), 3t3m(A).
		6. Ligand: NAG-NAG-BMA-MAN × 1 NAG=N-Acetyl-D-Glucosamine, BMA=Beta-D-Mannose, MAN=Alpha-D-Mannose. PDB code: 4cak(A).
		7. Ligand: NAG-NAG-MAN × 1 NAG=N-Acetyl-D-Glucosamine, MAN=Alpha-D-Mannose. PDB code: 3nig(A).
		8. Ligand: NAG-NAG-MAN-BMA × 1 NAG=N-Acetyl-D-Glucosamine, MAN=Alpha-D-Mannose, BMA=Beta-D-Mannose. PDB code: 1tye(A).

Cluster 3 contains 1 ligand type

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Ligand		Description
		1. Ligand: NAG-NAG-MAN-MAN-MAN × 1 NAG=N-Acetyl-D-Glucosamine, MAN=Alpha-D-Mannose. PDB code: 3fcs(A).

Cluster 4 contains 1 ligand type

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Ligand		Description
		1. Ligand: NAG-NAG-BMA × 1 NAG=N-Acetyl-D-Glucosamine, BMA=Beta-D-Mannose. PDB code: 4cak(A).

Cluster 5 contains 1 ligand type

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Ligand		Description
		1. Ligand: NAG-NAG × 1 NAG=N-Acetyl-D-Glucosamine. PDB code: 4cak(A).

Cluster 6 contains 2 ligand types

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Ligand		Description
		1. Ligand: GOL × 2 glycerin Glycerol PDB codes: 3nid(A), 3nif(A).
		2. Ligand: NAG × 1 n-acetylglucosamine N-Acetyl-D-Glucosamine PDB code: 4cak(A).