Ligand clusters for UniProt code P00383

Ligand clusters for P00383: Dihydrofolate reductase type 2 OS=Escherichia coli OX=562 PE=1 SV=1

		6 ligand clusters Cluster 1. 5 ligand types 6 ligands Cluster 2. 2 ligand types 7 ligands Cluster 3. 1 ligand type 10 ligands Cluster 4. 1 ligand type 1 ligand Cluster 5. 1 ligand type 1 ligand Cluster 6. 1 ligand type 1 ligand
Representative protein: 1vifA

Structures

PDB		Schematic diagram
1vifA
2rk1A
6nxzA
2rk2A
3sfmA
		more ...

Cluster 1 contains 5 ligand types

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Ligand		Description
		1. Ligand: NAP × 1 Nadp nicotinamide-Adenine-Dinucleotide phosphate PDB code: 2p4t(A).
		2. Ligand: FOL × 1 folic acid Folic acid PDB code: 1vif(A).
		3. Ligand: NAP × 2 Nadp nicotinamide-Adenine-Dinucleotide phosphate PDB codes: 2rk1(A), 2rk2(A).
		4. Ligand: D49 × 1 2-[4-[(2~{r})-4-[4-(6-Carboxy-1~{h}-Benzimidazol-2-Yl) phenoxy]-2-Oxidanyl-Butoxy]phenyl]-1~{h}- Benzimidazole-5-Carboxylic acid PDB code: 6nxz(A).
		5. Ligand: LBA × 1 2-(4-{3-[4-(6-Carboxy-1h-Benzimidazol-2-Yl)phenoxy]-2- Hydroxypropoxy}phenyl)-1h-Benzimidazole-5- Carboxylic acid PDB code: 6ny0(A).

Cluster 2 contains 2 ligand types

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Ligand		Description
		1. Ligand: MRD × 6 (4r)-2-Methylpentane-2,4-Diol PDB codes: 2rh2(A), 2rk1(A), 2rk2(A), 3sfm(A), 6nxz(A).
		2. Ligand: PO4 × 1 Phosphate ion PDB code: 6ny0(A).

Cluster 3 contains 1 ligand type

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Ligand		Description
		1. Ligand: MRD × 10 (4r)-2-Methylpentane-2,4-Diol PDB codes: 2rh2(A), 2rk1(A), 2rk2(A), 3sfm(A), 6nxz(A), 6ny0(A).

Cluster 4 contains 1 ligand type

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Ligand		Description
		1. Ligand: MRD × 1 (4r)-2-Methylpentane-2,4-Diol PDB code: 6ny0(A).

Cluster 5 contains 1 ligand type

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Ligand		Description
		1. Ligand: PO4 × 1 Phosphate ion PDB code: 6nxz(A).

Cluster 6 contains 1 ligand type

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Ligand		Description
		1. Ligand: PO4 × 1 Phosphate ion PDB code: 6ny0(A).