Ligand clusters for UniProt code O60218

Ligand clusters for O60218: Aldo-keto reductase family 1 member B10 OS=Homo sapiens OX=9606 GN=AKR1B10 PE=1 SV=2

		4 ligand clusters Cluster 1. 18 ligand types 38 ligands Cluster 2. 1 ligand type 9 ligands Cluster 3. 1 ligand type 1 ligand Cluster 4. 1 ligand type 1 ligand
Representative protein: 4gq0A

Structures

PDB		Schematic diagram
4gq0A
1zuaX
4gabA
4ga8A
5liuX
		more ...

Cluster 1 contains 18 ligand types

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Ligand		Description
		1. Ligand: FLF × 1 flufenamic acid 2-[[3-(Trifluoromethyl)phenyl]amino] benzoic acid PDB code: 4i5x(A).
		2. Ligand: SUZ × 1 sulindac [(1z)-5-Fluoro-2-Methyl-1-{4- [Methylsulfinyl]benzylidene}-1h-Inden-3-Yl]acetic acid PDB code: 4wev(X).
		3. Ligand: NAP × 20 Nadp nicotinamide-Adenine-Dinucleotide phosphate PDB codes: 1zua(X), 4ga8(A), 4gab(A), 4gq0(A), 4gqg(A), 4i5x(A), 4icc(X), 4jih(A), 4jii(X), 4wev(X), 4xzl(X), 4xzm(X), 4xzn(X), 5lik(X), 5liu(X), 5liw(X), 5lix(X), 5liy(X), 5m2f(X), 5y7n(A).
		4. Ligand: 1WX × 2 {2-[(4-Bromo-2,3,5,6-Tetrafluorobenzyl)carbamoyl]-5- Chlorophenoxy}acetic acid PDB codes: 5liw(X),
		5. Ligand: 388 × 1 (2-{[(4-Bromo-2-Fluorobenzyl)amino]carbonyl}-5- Chlorophenoxy)acetic acid PDB code: 5liu(X).
		6. Ligand: 64I × 1 2,2',3,3',5,5',6,6'-Octafluorobiphenyl-4,4'-Diol PDB code: 4icc(X).
		7. Ligand: 8QL × 1 (3s,6s,8s,9s,10r,13s,14r)-10,13-Dimethyl-2,3,6,7,8,9, 11,12,14,15,16,17-Dodecahydro-1h- Cyclopenta[a]phenanthrene-3,6-Diol PDB code: 5y7n(A).
		8. Ligand: DQP × 1 {5-Chloro-2-[(Pentabromobenzyl)carbamoyl]phenoxy}acetic acid PDB code: 5liy(X).
		9. Ligand: EPR × 1 {5-[(2e)-2-Methyl-3-Phenylprop-2-En-1-Ylidene]-4-Oxo-2- Thioxo-1,3-Thiazolidin-3-Yl}acetic acid PDB code: 4jih(A).
		10. Ligand: F49 × 1 [2,4-Dioxo-3-(2,3,4,5-Tetrabromo-6-Methoxybenzyl)-3,4- Dihydropyrimidin-1(2h)-Yl]acetic acid PDB code: 4xzl(X).
		11. Ligand: FID × 1 (2s,4s)-2-Aminoformyl-6-Fluoro-Spiro[chroman-4,4'- Imidazolidine]-2',5'-Dione PDB code: 4gab(A).
		12. Ligand: MK4 × 1 {5-Chloro-2-[(2,4,6-Tribromobenzyl) carbamoyl]phenoxy}acetic acid PDB code: 5lix(X).
		13. Ligand: QAP × 1 2-Phenylethyl (2e)-3-(3,4-Dihydroxyphenyl)prop-2-Enoate PDB code: 4gq0(A).
		14. Ligand: SBI × 1 Sorbinil PDB code: 4ga8(A).
		15. Ligand: TOL × 1 Tolrestat PDB code: 1zua(X).
		16. Ligand: UV8 × 1 3-Bromo-4-[(1e)-2-(5,5,8,8-Tetramethyl-5,6,7,8- Tetrahydronaphthalen-2-Yl)prop-1-En-1- Yl]benzoic acid PDB code: 5m2f(X).
		17. Ligand: W8X × 1 {2-[(4-Bromobenzyl)carbamoyl]-5-Chlorophenoxy}acetic acid PDB code: 5lik(X).
		18. Ligand: ZST × 1 3,4-Dihydro-4-Oxo-3-((5-Trifluoromethyl-2- Benzothiazolyl)methyl)-1-Phthalazine acetic acid PDB code: 4jii(X).

Cluster 2 contains 1 ligand type

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Ligand		Description
		1. Ligand: EDO × 9 1,2-Ethanediol PDB codes: 4xzl(X), 4xzm(X), 4xzn(X), 5lik(X), 5liu(X), 5liw(X), 5lix(X), 5liy(X), 5m2f(X).

Cluster 3 contains 1 ligand type

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Ligand		Description
_Cl		1. Metal: _CL × 1 PDB code: 4gab(A).

Cluster 4 contains 1 ligand type

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Ligand		Description
_Na		1. Metal: _NA × 1 PDB code: 4jii(X).