Ligand clusters for UniProt code O43924

Ligand clusters for O43924: Retinal rod rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit delta OS=Homo sapiens OX=9606 GN=PDE6D PE=1 SV=1

		2 ligand clusters Cluster 1. 22 ligand types 30 ligands Cluster 2. 1 ligand type 2 ligands
Representative protein: 5nalB

Structures

PDB		Schematic diagram
5nalB
5yavB
5ml4B
5yawB
5x73A
		more ...

Cluster 1 contains 22 ligand types (of which only 20 are listed. Click for all)

Use checkboxes to select ligands to display in RasMol, Jmol, or download as an SDF file. Selection shortcuts: select all/none invert selection.
Ligand		Description
		1. Ligand: FAR × 5 Farnesyl PDB codes: 3t5g(B), 3t5i(B), 5tar(B), 5tb5(B).
		2. Ligand: P59 × 3 (2r)-2-(2-Fluorophenyl)-3-Phenyl-1,2-Dihydroquinazolin- 4-One PDB codes: 5x72(A), 5x73(A),
		3. Ligand: 18F × 2 1-Benzyl-2-Phenyl-1h-Benzimidazole PDB codes: 4jv6(B),
		4. Ligand: 1M1 × 2 (6r)-6-(Pyridin-2-Yl)-5,6-Dihydrobenzimidazo[1,2- C]quinazoline PDB codes: 4jv8(B),
		5. Ligand: 17X × 1 (2s)-2-(2-Phenyl-1h-Benzimidazol-1-Yl)-2-(Piperidin-4- Yl)ethyl 1-(1-Benzyl-1h-Benzimidazol-2- Yl)piperidine- 4-Carboxylate PDB code: 4jvf(B).
		6. Ligand: 1M0 × 1 1-Benzyl-2-(4-{[(2r)-2-(2-Phenyl-1h-Benzimidazol-1-Yl) pent-4-En-1-Yl]oxy}phenyl)-1h-Benzimidazole PDB code: 4jvb(B).
		7. Ligand: 5KP × 1 N-(3-Chloro-2-Methylphenyl)-4-(3,4-Dimethyl-7-Oxo-2- Phenyl-2,7-Dihydro-6h-Pyrazolo[3,4- D]pyridazin-6-Yl) butanamide PDB code: 5e80(B).
		8. Ligand: 8RQ × 1 ~{N}4-[(4-Chlorophenyl)methyl]-~{N}1- (Cyclohexylmethyl)-~{N}4-Cyclopentyl-~{N}1-[(~{Z})-4- [(~{E})-Methyliminomethyl]-5-Oxidanyl-Hex-4- Enyl]benzene-1,4-Disulfonamide PDB code: 5nal(B).
		9. Ligand: 8SF × 1 1-Phenyl-5-Propan-2-Ylsulfanyl-1,2,3,4-Tetrazole PDB code: 5yav(B).
		10. Ligand: 8SL × 1 3-[(4-Methoxyphenyl)methylsulfanyl]-5-(2-Methylpropyl)- 4-(Phenylmethyl)-1,2,4-Triazole PDB code: 5yaw(B).
		11. Ligand: 9GD × 1 2-Azanyl-4-[[[4-[(4-Chlorophenyl)methyl-Cyclopentyl- Sulfamoyl]phenyl]sulfonyl-(Piperidin-4- Ylmethyl) amino]methyl]benzoic acid PDB code: 5ml6(B).
		12. Ligand: CMT-FAR × 1 CMT=O-Methylcysteine, FAR=Farnesyl. PDB code: 5f2u(A).
		13. Ligand: DL3 × 1 ~{N}1-[(4-Chlorophenyl)methyl]-~{N}1-Cyclopentyl-~{N}4- [[2-(Methylamino)pyrimidin-4-Yl]methyl]- ~{N}4- (Piperidin-4-Ylmethyl)benzene-1,4-Disulfonamide PDB code: 5ml3(B).
		14. Ligand: GER × 1 Geran-8-Yl geran PDB code: 5e8f(A).
		15. Ligand: JAY × 1 (2r)-2-(2-Fluorophenyl)-3-[2-[4-[(2r)-2-(2- Fluorophenyl)-4-Oxidanylidene-1,2-Dihydroquinazolin-3- Yl]piperidin-1-Yl]ethyl]-1,2-Dihydroquinazolin-4-One PDB code: 5x74(A).
		16. Ligand: LYS-SER-LYS-THR-CMT × 1 CMT=O-Methylcysteine. PDB code: 5e8f(A).
		17. Ligand: NH6 × 1 ~{N}1-[(4-Chlorophenyl)methyl]-~{N}1-Cyclopentyl-~{N}4- (Phenylmethyl)benzene-1,4-Disulfonamide PDB code: 5ml2(B).
		18. Ligand: P69 × 1 (2s)-2-(2-Fluorophenyl)-3-Phenyl-1,2-Dihydroquinazolin- 4-One PDB code: 5x72(A).
		19. Ligand: RRQ × 1 4-[[[4-[(4-Chlorophenyl)methyl-Cyclopentyl- Sulfamoyl]phenyl]sulfonyl-(Piperidin-4- Ylmethyl) amino]methyl]-2-(Methylamino)benzoic acid PDB code: 5ml4(B).
		20. Ligand: SER-SER-CMT × 1 CMT=O-Methylcysteine. PDB code: 3t5i(A).
+ more. Press for full list

Cluster 2 contains 1 ligand type

Selection shortcuts: select all/none invert selection.
Ligand		Description
		1. Ligand: EDO × 2 1,2-Ethanediol PDB codes: 5tar(B), 5tb5(B).