Ligand clusters for UniProt code O43570

Ligand clusters for O43570: Carbonic anhydrase 12 from Homo sapiens

		Top 6 (of 19) ligand clusters Cluster 1. 29 ligand types 61 ligands Cluster 2. 2 ligand types 2 ligands Cluster 3. 2 ligand types 2 ligands Cluster 4. 1 ligand type 1 ligand Cluster 5. 1 ligand type 3 ligands Cluster 6. 1 ligand type 1 ligand
Representative protein: 6g7aA

Structures

PDB		Schematic diagram
6g7aA
6rpsA
5lloA
1jczA
6t5pA
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Cluster 1 contains 29 ligand types (of which only 20 are listed. Click for all)

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Ligand		Description
_Zn		1. Metal: _ZN × 26 PDB codes: 1jcz(A), 1jd0(A), 4ht2(A), 4kp5(A), 4kp8(A), 4q0l(A), 4qj0(A), 4qjo(A), 4qjw(A), 4ww8(A), 5ll5(A), 5ll9(A), 5llo(A), 5llp(A), 5msa(A), 5msb(A), 6g5l(A), 6g7a(A), 6qn0(A), 6qng(A), 6qnl(A), 6r6y(A), 6r71(A), 6rps(A), 6t5p(A), 6t5q(A).
		2. Ligand: ACY × 1 acetic acid Acetic acid PDB code: 1jcz(A).
		3. Ligand: AZM × 1 acetazolamide 5-Acetamido-1,3,4-Thiadiazole-2-Sulfonamide PDB code: 1jd0(A).
		4. Ligand: EDO × 7 1,2-Ethanediol PDB codes: 4ht2(A), 4kp5(A), 4ww8(A), 5ll5(A), 5ll9(A),
		5. Ligand: PEG × 2 Di(hydroxyethyl)ether PDB codes: 4ht2(A), 6g5l(A).
		6. Ligand: 3TV × 1 2,3,5,6-Tetrafluoro-4-(Propylsulfanyl) benzenesulfonamide PDB code: 5msa(A).
		7. Ligand: 5EF × 1 3-[(1s)-2,3-Dihydro-1h-Inden-1-Ylamino]-2,5,6- Trifluoro-4-[(2- Hydroxyethyl) sulfonyl]benzenesulfonamide PDB code: 5llo(A).
		8. Ligand: 6YH × 1 4-[2-(Benzimidazol-1-Yl)ethanoyl]benzenesulfonamide PDB code: 5ll5(A).
		9. Ligand: 6YQ × 1 4-[2-(Benzimidazol-1-Yl)ethanoyl]-2-Chloranyl- Benzenesulfonamide PDB code: 5ll9(A).
		10. Ligand: 6Z9 × 1 3-[(1s)-1,2,3,4-Tetrahydronapthalen-1-Ylamino)-2,5,6- Trifluoro-4-[(2- Hydroxyethyl) sulfonyl]benzenesulfonamide PDB code: 5llp(A).
		11. Ligand: ACT × 1 Acetate ion PDB code: 6rps(A).
		12. Ligand: E1F × 1 2-Chloro-4-[(Pyrimidin-2-Ylsulfanyl) acetyl]benzenesulfonamide PDB code: 4kp5(A).
		13. Ligand: E1G × 1 3-[(Pyrimidin-2-Ylsulfanyl)acetyl]benzenesulfonamide PDB code: 4kp8(A).
		14. Ligand: EA3 × 1 4-Chloranyl-2-Cyclohexylsulfanyl-~{N}-(2-Hydroxyethyl)- 5-Sulfamoyl-Benzamide PDB code: 6r6y(A).
		15. Ligand: EM5 × 1 4-Chloranyl-2-(Cyclohexylamino)-~{N}-(2-Hydroxyethyl)- 5-Sulfamoyl-Benzamide PDB code: 6g5l(A).
		16. Ligand: EOQ × 1 4-Chloranyl-~{N}-(2-Hydroxyethyl)-2-[(Phenylmethyl) amino]-5-Sulfamoyl-Benzamide PDB code: 6g7a(A).
		17. Ligand: J8Q × 1 ~{N}-Butyl-4-Chloranyl-2-(2-Phenylethylsulfanyl)-5- Sulfamoyl-Benzamide PDB code: 6qn0(A).
		18. Ligand: J92 × 1 Methyl 4-[(4-Chloranyl-2-Cyclohexylsulfanyl-5- Sulfamoyl-Phenyl)carbonylamino]butanoate PDB code: 6qnl(A).
		19. Ligand: J95 × 1 ~{N}-Butyl-4-Chloranyl-2-(Cyclohexylamino)-5-Sulfamoyl- Benzamide PDB code: 6qng(A).
		20. Ligand: JTW × 1 4-Chloranyl-~{N}-(2-Hydroxyethyl)-2-(Phenylsulfonyl)-5- Sulfamoyl-Benzamide PDB code: 6r71(A).
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Cluster 2 contains 2 ligand types

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Ligand		Description
		1. Ligand: DMS × 1 dimethyl sulfoxide Dimethyl sulfoxide PDB code: 4kp8(A).
		2. Ligand: PEG × 1 Di(hydroxyethyl)ether PDB code: 5msa(A).

Cluster 3 contains 2 ligand types

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Ligand		Description
		1. Ligand: DMS × 1 dimethyl sulfoxide Dimethyl sulfoxide PDB code: 6r6y(A).
		2. Ligand: EDO × 1 1,2-Ethanediol PDB code: 5msb(A).

Cluster 4 contains 1 ligand type

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Ligand		Description
		1. Ligand: SO4 × 1 Sulfate ion PDB code: 6rps(A).

Cluster 5 contains 1 ligand type

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Ligand		Description
		1. Ligand: EDO × 3 1,2-Ethanediol PDB codes: 4ht2(A), 4qjw(A), 5ll9(A).

Cluster 6 contains 1 ligand type

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Ligand		Description
		1. Ligand: EDO × 1 1,2-Ethanediol PDB code: 4ht2(A).