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Figure 6.
Figure 6. Surface Representation of Prolyl
OligopeptidaseThe molecular surface is superimposed on the
polypeptide chain. The picture shows a slab of the molecule,
hence the cropping of the chain. The large cavity extends from
the central tunnel of the β propeller to the catalytic domain
and is accessible through the narrow hole at the bottom of the
propeller. The covalently bound inhibitor, Z-Pro-prolinal, is
shown in a ball-and-stick representation. The molecular surface
was calculated by the method published by [11], and the figure
was prepared using XOBJECTS (M. E. M. Noble, Oxford, unpublished
program).
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