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Figure 3.
Figure 3: Transmembrane Ca^2+-binding sites (I and II) and the
movement of the M1 helix.
a, E1  2Ca^2+;
b, E1 AMPPCP;
c, superimposition of E1 2Ca^2+
(violet) and E1 AMPPCP
(atom colour) in stereo view. Cyan (a–c) and violet spheres
(c) represent bound Ca^2+; red spheres indicate water molecules
in the crystals. Owing to the resolution limitation of the
diffraction data, no water molecules are shown in b. Dotted
lines in c show the coordination of Ca^2+ and hydrogen bonds
involving E309 and D800 side chains.
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