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Figure 3.
Figure 3. Correlation of ΔΔASA[HP] (changes in
hydrophobic surface area exposed upon denaturation) with ΔΔG
for the mutant proteins with empty cavities (a) and with
solvated cavities (b). The mutants with solvated cavities are
shown as open symbols and labeled. The mutants of the type I are
represented by black filled up-triangles (with empty cavity).
The black continuous line shows the linear regression of the
type I mutants with empty cavity (black filled up-triangles).
The mutants of the type II are represented by blue filled (with
empty cavity) and open (with solvated cavity) circles. The blue
broken line shows the linear regression of the type II mutants
with solvated cavity (blue open circles). The mutants of the
type III are represented by red filled (with empty cavity) and
open (with solvated cavity) squares. The red continuous line
shows the linear regression of the type III mutants with empty
cavity (red filled squares). The red broken line is drawn with
reference to the red continuous line. The ASA values were
calculated using the procedure of [Connolly 1993].
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