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Figure 1.
Figure 1. Stereo view comparing the structures of
crystallographically distinct monomers. Superpositions were
carried out with the program LSQKAB.27 Monomers A, B and C of
PAF-GM2-AP are shown in cyan, blue and magenta, respectively.
The flexible reverse turn P129 to L132 is labeled mobile loop.
The protruding loop V59 to W63, thought to interact with lipid
bilayers, is labeled apolar loop. Monomer C of the apo structure
is shown superimposed in yellow, illustrating the rotated
position of the mobile loop with insertion of W131 into the
cleft. N and C refer to the amino and carboxy terminal ends of
the polypeptide chain. The position of the chloride ion (CL) is
indicated. Sequence numbering refers to the mature protein of
162 amino acid residues. The Figure was generated with Dino
(http://cobra.mih.unibas.ch/dino).
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