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Figure 5.
Figure 5: Extracellular and cytoplasmic gates. a, Slice
through the surface of LeuT[Aa], viewed parallel to the
membrane, showing the extracellular cavity. Connolly surface of
LeuT[Aa] is shown in beige. l-Leucine, Tyr 108, Phe 253 and the
two charged pairs (Arg 30 -Asp 404 and Arg 5 -Asp 369) are
depicted as stick models in yellow for leucine, purple for
aromatic residues, blue for arginines and red for aspartates. b,
c, Key interacting residues at the extracellular (b) and at the
cytoplasmic (c) gate.
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