Figure 5.
Figure 5: Conformation changes around the Ca^2+-binding sites.
a, C trace
and the side chains of the coordinating residues in E1Ca^2+. b,
Composite omit map37 (at 1.2 )
and the model for the corresponding area in E2(TG). c, Stereo
view of the composite of the models for E1Ca^2+ (violet) and
E2(TG) (atom colour). The viewing direction is approximately
down the M5 helix in E1Ca^2+. Two bound Ca^2+ appear as cyan
spheres (a) or circles (c). Dashed lines in b show potential
hydrogen bonds. Orange arrows in c show the movements of the
corresponding residues during the change from E1Ca^2+ to E2(TG).
trace
and the side chains of the coordinating residues in E1Ca^2+. b,
Composite omit map37 (at 1.2 
)
and the model for the corresponding area in E2(TG). c, Stereo
view of the composite of the models for E1Ca^2+ (violet) and
E2(TG) (atom colour). The viewing direction is approximately
down the M5 helix in E1Ca^2+. Two bound Ca^2+ appear as cyan
spheres (a) or circles (c). Dashed lines in b show potential
hydrogen bonds. Orange arrows in c show the movements of the
corresponding residues during the change from E1Ca^2+ to E2(TG).