Figure 3 - full size

Figure 3.
Figure 3. The charge distribution of s-Sec1. Surface potential representations of s-Sec1 colored according to electrostatic potential: < -10 k[B]T, red; > + 10 k[B]T, blue (k[B], Boltzmann constant; T, absolute temperature). Exposed residues are labeled with the sequence number. (a) s-Sec1 rotated by approximately 90° (with respect to the orientation in (b)) to indicate the negatively charged interface of domains I and II. (b) The orientation of the molecule corresponds approximately to the one shown in Figure 2a; it shows a prominent negatively charged groove within the central part of the molecule. The figures were generated using the program GRASP [77].